NEW KNOWLEDGE ABOUT THE SJOGREN SYNDROME
The Sjogren syndrome is a clinic-pathological unit characterized by dry eyes(keratoconjunctivitis sicca) and dry mouth (xerostomia). It can be solitary or acomplication of other auto-immune disease. A complex clinic symptomatology, anincreasing frequency of the Sjogren syndrome, a still difficult ti...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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University in Nis, Faculty of Medicine
2001-09-01
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| Series: | Acta Medica Medianae |
| Subjects: | |
| Online Access: | http://publisher.medfak.ni.ac.rs/2001-html/5-broj-2001/NOVA%20SAZNANJA%20O%20SJOGREN-OVOM....pdf |
| _version_ | 1818215799606738944 |
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| author | Predrag Jovanovic Gordana Stankovic-Babic Gordana Zlatanović Sonja Zivkovic Vuka Katic |
| author_facet | Predrag Jovanovic Gordana Stankovic-Babic Gordana Zlatanović Sonja Zivkovic Vuka Katic |
| author_sort | Predrag Jovanovic |
| collection | DOAJ |
| description | The Sjogren syndrome is a clinic-pathological unit characterized by dry eyes(keratoconjunctivitis sicca) and dry mouth (xerostomia). It can be solitary or acomplication of other auto-immune disease. A complex clinic symptomatology, anincreasing frequency of the Sjogren syndrome, a still difficult timely detection, somenew knowledge about the pathogenic mechanisms as well as a new approach to itstreatment - these are all the reasons for the histologic and histochemical examination of the operation material of the salivary gland primarily from the standpoint of ahistologic detection of the immunological markers. The operation material fixationwas done in formalin, while the laboratory treatment of the tissue in the autotechnicon.The laboratory sections were dyed with classical and histochemicalpainting methods. In all the patients the dominant were tumefactions in the parotidgland region, with less prominent kerastomy, while the eye changes were slight. Inthe histologic way the periacinous and the periduct lymphoplasmocyte infiltrationwas found as well as hyperplasia of the lymph follicles joined with hyperplasia oftheir germination centers. The setting-up of the diagnosis not earlier then at thesalivary gland's operation material points to a very complex clinic symptomatologyas well as to insufficient experience of the physicians due to formerly very rare whiletoday all the more frequent Sjogren syndrome. |
| first_indexed | 2024-12-12T06:41:49Z |
| format | Article |
| id | doaj.art-3b72f56b68314b35b90e462eaa70d064 |
| institution | Directory Open Access Journal |
| issn | 0365-4478 |
| language | English |
| last_indexed | 2024-12-12T06:41:49Z |
| publishDate | 2001-09-01 |
| publisher | University in Nis, Faculty of Medicine |
| record_format | Article |
| series | Acta Medica Medianae |
| spelling | doaj.art-3b72f56b68314b35b90e462eaa70d0642022-12-22T00:34:18ZengUniversity in Nis, Faculty of MedicineActa Medica Medianae0365-44782001-09-014052330NEW KNOWLEDGE ABOUT THE SJOGREN SYNDROMEPredrag JovanovicGordana Stankovic-BabicGordana ZlatanovićSonja ZivkovicVuka KaticThe Sjogren syndrome is a clinic-pathological unit characterized by dry eyes(keratoconjunctivitis sicca) and dry mouth (xerostomia). It can be solitary or acomplication of other auto-immune disease. A complex clinic symptomatology, anincreasing frequency of the Sjogren syndrome, a still difficult timely detection, somenew knowledge about the pathogenic mechanisms as well as a new approach to itstreatment - these are all the reasons for the histologic and histochemical examination of the operation material of the salivary gland primarily from the standpoint of ahistologic detection of the immunological markers. The operation material fixationwas done in formalin, while the laboratory treatment of the tissue in the autotechnicon.The laboratory sections were dyed with classical and histochemicalpainting methods. In all the patients the dominant were tumefactions in the parotidgland region, with less prominent kerastomy, while the eye changes were slight. Inthe histologic way the periacinous and the periduct lymphoplasmocyte infiltrationwas found as well as hyperplasia of the lymph follicles joined with hyperplasia oftheir germination centers. The setting-up of the diagnosis not earlier then at thesalivary gland's operation material points to a very complex clinic symptomatologyas well as to insufficient experience of the physicians due to formerly very rare whiletoday all the more frequent Sjogren syndrome.http://publisher.medfak.ni.ac.rs/2001-html/5-broj-2001/NOVA%20SAZNANJA%20O%20SJOGREN-OVOM....pdfSjogren syndromepathogenesisclinicmorfology |
| spellingShingle | Predrag Jovanovic Gordana Stankovic-Babic Gordana Zlatanović Sonja Zivkovic Vuka Katic NEW KNOWLEDGE ABOUT THE SJOGREN SYNDROME Acta Medica Medianae Sjogren syndrome pathogenesis clinic morfology |
| title | NEW KNOWLEDGE ABOUT THE SJOGREN SYNDROME |
| title_full | NEW KNOWLEDGE ABOUT THE SJOGREN SYNDROME |
| title_fullStr | NEW KNOWLEDGE ABOUT THE SJOGREN SYNDROME |
| title_full_unstemmed | NEW KNOWLEDGE ABOUT THE SJOGREN SYNDROME |
| title_short | NEW KNOWLEDGE ABOUT THE SJOGREN SYNDROME |
| title_sort | new knowledge about the sjogren syndrome |
| topic | Sjogren syndrome pathogenesis clinic morfology |
| url | http://publisher.medfak.ni.ac.rs/2001-html/5-broj-2001/NOVA%20SAZNANJA%20O%20SJOGREN-OVOM....pdf |
| work_keys_str_mv | AT predragjovanovic newknowledgeaboutthesjogrensyndrome AT gordanastankovicbabic newknowledgeaboutthesjogrensyndrome AT gordanazlatanovic newknowledgeaboutthesjogrensyndrome AT sonjazivkovic newknowledgeaboutthesjogrensyndrome AT vukakatic newknowledgeaboutthesjogrensyndrome |