Genetic characterization of infectious bronchitis viruses in Thailand, 2014–2016: identification of a novel recombinant variant
Infectious bronchitis (IB) causes severe economic losses to the poultry industry worldwide owing to frequent emergence of novel infectious bronchitis virus (IBV) variants, which potentially affect the effectiveness of the currently used IBV vaccine. Therefore, continuous monitoring of IBV genotypes...
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| Format: | Article |
| Language: | English |
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Elsevier
2020-04-01
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| Series: | Poultry Science |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0032579119578415 |
| _version_ | 1811225811014909952 |
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| author | Sirorat Munyahongse Tawatchai Pohuang Nutthawan Nonthabenjawan Jiroj Sasipreeyajan Aunyaratana Thontiravong |
| author_facet | Sirorat Munyahongse Tawatchai Pohuang Nutthawan Nonthabenjawan Jiroj Sasipreeyajan Aunyaratana Thontiravong |
| author_sort | Sirorat Munyahongse |
| collection | DOAJ |
| description | Infectious bronchitis (IB) causes severe economic losses to the poultry industry worldwide owing to frequent emergence of novel infectious bronchitis virus (IBV) variants, which potentially affect the effectiveness of the currently used IBV vaccine. Therefore, continuous monitoring of IBV genotypes and lineages recently circulating in chickens worldwide is essential. In this study, we characterized the complete S1 gene from 120 IBVs circulating in chickens in Thailand from 2014 to 2016. Phylogenetic analysis of the complete S1 gene of 120 Thai IBVs revealed that the 2014–2016 Thai IBVs were divided into 3 lineages (GI-1, GI-13, and GI-19) and a novel IBV variant. Our results also showed that GI-19 lineage has become the predominant lineage of IBV circulating in chicken flocks in Thailand from 2014 to 2016. It is interesting to note that a novel IBV variant, which was genetically different from the established IBV lineages, was identified in this study. The recombination analysis demonstrated that this novel IBV variant was a recombinant virus, which was originated from the GI-19 and GI-13 lineage viruses. In conclusion, our data demonstrate the circulation of different lineages of IBV and the presence of a novel recombinant IBV variant in chicken flocks in Thailand. This study highlights the high genetic diversity and continued evolution of IBVs in chickens in Thailand, and the importance of continued IBV surveillance for effective control and prevention of IB. |
| first_indexed | 2024-04-12T09:14:44Z |
| format | Article |
| id | doaj.art-3b73496011fb469485f4fc6b1e7f3a0f |
| institution | Directory Open Access Journal |
| issn | 0032-5791 |
| language | English |
| last_indexed | 2024-04-12T09:14:44Z |
| publishDate | 2020-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Poultry Science |
| spelling | doaj.art-3b73496011fb469485f4fc6b1e7f3a0f2022-12-22T03:38:53ZengElsevierPoultry Science0032-57912020-04-0199418881895Genetic characterization of infectious bronchitis viruses in Thailand, 2014–2016: identification of a novel recombinant variantSirorat Munyahongse0Tawatchai Pohuang1Nutthawan Nonthabenjawan2Jiroj Sasipreeyajan3Aunyaratana Thontiravong4Department of Veterinary Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, ThailandResearch Group for Animal Health Technology, Department of Veterinary Medicine, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen, ThailandEmerging and Re-emerging Infectious Diseases in Animals (CUEIDAs), Center of Excellence, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, ThailandAvian Health Research Unit, Department of Veterinary Medicine, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, ThailandDepartment of Veterinary Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand; Emerging and Re-emerging Infectious Diseases in Animals (CUEIDAs), Center of Excellence, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand; Corresponding author:Infectious bronchitis (IB) causes severe economic losses to the poultry industry worldwide owing to frequent emergence of novel infectious bronchitis virus (IBV) variants, which potentially affect the effectiveness of the currently used IBV vaccine. Therefore, continuous monitoring of IBV genotypes and lineages recently circulating in chickens worldwide is essential. In this study, we characterized the complete S1 gene from 120 IBVs circulating in chickens in Thailand from 2014 to 2016. Phylogenetic analysis of the complete S1 gene of 120 Thai IBVs revealed that the 2014–2016 Thai IBVs were divided into 3 lineages (GI-1, GI-13, and GI-19) and a novel IBV variant. Our results also showed that GI-19 lineage has become the predominant lineage of IBV circulating in chicken flocks in Thailand from 2014 to 2016. It is interesting to note that a novel IBV variant, which was genetically different from the established IBV lineages, was identified in this study. The recombination analysis demonstrated that this novel IBV variant was a recombinant virus, which was originated from the GI-19 and GI-13 lineage viruses. In conclusion, our data demonstrate the circulation of different lineages of IBV and the presence of a novel recombinant IBV variant in chicken flocks in Thailand. This study highlights the high genetic diversity and continued evolution of IBVs in chickens in Thailand, and the importance of continued IBV surveillance for effective control and prevention of IB.http://www.sciencedirect.com/science/article/pii/S0032579119578415chickengenetic characterizationinfectious bronchitis virusThailand |
| spellingShingle | Sirorat Munyahongse Tawatchai Pohuang Nutthawan Nonthabenjawan Jiroj Sasipreeyajan Aunyaratana Thontiravong Genetic characterization of infectious bronchitis viruses in Thailand, 2014–2016: identification of a novel recombinant variant Poultry Science chicken genetic characterization infectious bronchitis virus Thailand |
| title | Genetic characterization of infectious bronchitis viruses in Thailand, 2014–2016: identification of a novel recombinant variant |
| title_full | Genetic characterization of infectious bronchitis viruses in Thailand, 2014–2016: identification of a novel recombinant variant |
| title_fullStr | Genetic characterization of infectious bronchitis viruses in Thailand, 2014–2016: identification of a novel recombinant variant |
| title_full_unstemmed | Genetic characterization of infectious bronchitis viruses in Thailand, 2014–2016: identification of a novel recombinant variant |
| title_short | Genetic characterization of infectious bronchitis viruses in Thailand, 2014–2016: identification of a novel recombinant variant |
| title_sort | genetic characterization of infectious bronchitis viruses in thailand 2014 2016 identification of a novel recombinant variant |
| topic | chicken genetic characterization infectious bronchitis virus Thailand |
| url | http://www.sciencedirect.com/science/article/pii/S0032579119578415 |
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