Effect of selective β-blockers on spirometry in a 4 hour bronchial provocation test in patients with bronchoobstructive pathology
Administration of β-blockers in patients with cardiovascular pathology combined with obstructive bronchial or pulmonary disease (bronchial asthma (BA) and chronic obstructive pulmonary disease (COPD)) is associated with a risk of bronchospasm in a number of patients. No test has been developed so fa...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Remedium Group LLC
2014-12-01
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| Series: | Медицинский совет |
| Subjects: | |
| Online Access: | https://www.med-sovet.pro/jour/article/view/770 |
| Summary: | Administration of β-blockers in patients with cardiovascular pathology combined with obstructive bronchial or pulmonary disease (bronchial asthma (BA) and chronic obstructive pulmonary disease (COPD)) is associated with a risk of bronchospasm in a number of patients. No test has been developed so far to identify such patients. We recommend to carry out a 4-hour bronchial provocation test with a small dose of beta 1 selective β-blocker bisoprolol. The study included 31 patients with BA and COPD with concomitant cardiovascular disease requiring administration of β-blockers. Results of six consecutive spirometry tests, which continued for 4 hours to assess the effect of bisoprolol on airway function, are demonstrated. The maximum reduction in FEV1 after administration of the β-blocker was identified. Spirometry test results were compared in patients with BA and COPD. |
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| ISSN: | 2079-701X 2658-5790 |