Identification of novel B-1 transitional progenitors by B-1 lymphocyte fate-mapping transgenic mouse model Bhlhe41dTomato-Cre

Identification of novel B-1 transitional progenitors by B-1 lymphocyte fate-mapping transgenic mouse model Bhlhe41dTomato-Cre

B-1 lymphocytes exhibit specialized roles in host defense against multiple pathogens. Despite the fact that CD19+CD93+B220lo/- B cells have been identified as B-1 progenitors, the definition for B-1 progenitors remains to be elucidated as CD19+CD93+B220+ B cells are capable to give rise to B-1 cells...

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Bibliographic Details
Main Authors: Hui Li, Yangyang Tang, Jinfeng Ren, Ruixue Bai, Lang Hu, Wenyu Jia, Yiwei Cao, Li Hong, Meizhen Xu, Sijia Gao, Yanbiao Shi, Shuai Pan, Liang Wang, Kuiyang Zheng, Shuli Zhao, Hui Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
B-1
B-1 progenitors
fate mapping
Bhlhe41
dTomato
EYFP
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.946202/full

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