Impaired selective attention in patients with severe primary monosymptomatic nocturnal enuresis: An event-related potential study
Objectives: Primary monosymptomatic nocturnal enuresis (PMNE) is a very common problem in school age children. It is thought that PMNE represents a maturational lag in the central nervous system of those children. We did this case control study to assess the selective attention and resource allocati...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-01-01
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| Series: | Clinical Neurophysiology Practice |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2467981X2100041X |
| _version_ | 1818353026463694848 |
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| author | Mohamed N. Thabit Ahmed M. Abd Elhamed |
| author_facet | Mohamed N. Thabit Ahmed M. Abd Elhamed |
| author_sort | Mohamed N. Thabit |
| collection | DOAJ |
| description | Objectives: Primary monosymptomatic nocturnal enuresis (PMNE) is a very common problem in school age children. It is thought that PMNE represents a maturational lag in the central nervous system of those children. We did this case control study to assess the selective attention and resource allocation in those children using the P300 wave of the Event-Related Potentials (ERPs) and its relation to disease severity. Methods: Forty four patients with PMNE and twenty three healthy controls were included in this study. Patients were diagnosed according to the criteria of international children’s continence society and were classified into two groups; patients with frequent wetting (≥4 episodes/week), and patients with infrequent wetting (<4 episodes/week). ERPs were recorded at Fz, Cz, and Pz locations using odd-ball paradigm. N200 and P300 peak latencies (ms), and N200/P300 peak to peak amplitudes (µV) were measured. Results: We found significant increase of P300 and N200/P300 interpeak latencies, and significant decrease of P300 amplitudes in frequent wetting group “severe” PMNE compared to healthy controls and infrequent wetting group. Conclusion: Abnormal selective attention and resource allocation were found in patients with severe PMNE. Measures to improve selective attention might be helpful in treatment of patients with severe PMNE. Significance: Impaired selective attention might play a role in pathogenesis of severe PMNE and the need for the various measures to improve selective attention may be further studied as a therapeutic tool for patients with severe PMNE. |
| first_indexed | 2024-12-13T19:02:59Z |
| format | Article |
| id | doaj.art-3b75bccdf80149be9c95f2daa1601a9c |
| institution | Directory Open Access Journal |
| issn | 2467-981X |
| language | English |
| last_indexed | 2024-12-13T19:02:59Z |
| publishDate | 2021-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Clinical Neurophysiology Practice |
| spelling | doaj.art-3b75bccdf80149be9c95f2daa1601a9c2022-12-21T23:34:38ZengElsevierClinical Neurophysiology Practice2467-981X2021-01-016260264Impaired selective attention in patients with severe primary monosymptomatic nocturnal enuresis: An event-related potential studyMohamed N. Thabit0Ahmed M. Abd Elhamed1Department of Neurology, Sohag Faculty of Medicine, Sohag University, Sohag, Egypt; Corresponding author at: Department of Neurology, Sohag University Hospital, Sohag University, Madinat, Nasser, Sohag 82524, Egypt.Department of Urology, Sohag Faculty of Medicine, Sohag University, Sohag, EgyptObjectives: Primary monosymptomatic nocturnal enuresis (PMNE) is a very common problem in school age children. It is thought that PMNE represents a maturational lag in the central nervous system of those children. We did this case control study to assess the selective attention and resource allocation in those children using the P300 wave of the Event-Related Potentials (ERPs) and its relation to disease severity. Methods: Forty four patients with PMNE and twenty three healthy controls were included in this study. Patients were diagnosed according to the criteria of international children’s continence society and were classified into two groups; patients with frequent wetting (≥4 episodes/week), and patients with infrequent wetting (<4 episodes/week). ERPs were recorded at Fz, Cz, and Pz locations using odd-ball paradigm. N200 and P300 peak latencies (ms), and N200/P300 peak to peak amplitudes (µV) were measured. Results: We found significant increase of P300 and N200/P300 interpeak latencies, and significant decrease of P300 amplitudes in frequent wetting group “severe” PMNE compared to healthy controls and infrequent wetting group. Conclusion: Abnormal selective attention and resource allocation were found in patients with severe PMNE. Measures to improve selective attention might be helpful in treatment of patients with severe PMNE. Significance: Impaired selective attention might play a role in pathogenesis of severe PMNE and the need for the various measures to improve selective attention may be further studied as a therapeutic tool for patients with severe PMNE.http://www.sciencedirect.com/science/article/pii/S2467981X2100041XNocturnal enuresisEvent-related potentialsP300Attention |
| spellingShingle | Mohamed N. Thabit Ahmed M. Abd Elhamed Impaired selective attention in patients with severe primary monosymptomatic nocturnal enuresis: An event-related potential study Clinical Neurophysiology Practice Nocturnal enuresis Event-related potentials P300 Attention |
| title | Impaired selective attention in patients with severe primary monosymptomatic nocturnal enuresis: An event-related potential study |
| title_full | Impaired selective attention in patients with severe primary monosymptomatic nocturnal enuresis: An event-related potential study |
| title_fullStr | Impaired selective attention in patients with severe primary monosymptomatic nocturnal enuresis: An event-related potential study |
| title_full_unstemmed | Impaired selective attention in patients with severe primary monosymptomatic nocturnal enuresis: An event-related potential study |
| title_short | Impaired selective attention in patients with severe primary monosymptomatic nocturnal enuresis: An event-related potential study |
| title_sort | impaired selective attention in patients with severe primary monosymptomatic nocturnal enuresis an event related potential study |
| topic | Nocturnal enuresis Event-related potentials P300 Attention |
| url | http://www.sciencedirect.com/science/article/pii/S2467981X2100041X |
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