Syringomyelia diagnosed with leprosy: A case report

Leprosy has high incidence in tropical and subtropical countries. We document a case of 26-year-old female with an 18-month history of insidious onset progressive weakness and wasting of small muscles of both hands with decreased sensation distal to elbows and trophic changes without thickened nerve...

Full description

Bibliographic Details
Main Authors: Vijay Sardana, Rahi Kiran Bhattiprolu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Clinical Dermatology Review
Subjects:
Online Access:http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2019;volume=3;issue=2;spage=136;epage=138;aulast=Sardana
_version_ 1818607087940272128
author Vijay Sardana
Rahi Kiran Bhattiprolu
author_facet Vijay Sardana
Rahi Kiran Bhattiprolu
author_sort Vijay Sardana
collection DOAJ
description Leprosy has high incidence in tropical and subtropical countries. We document a case of 26-year-old female with an 18-month history of insidious onset progressive weakness and wasting of small muscles of both hands with decreased sensation distal to elbows and trophic changes without thickened nerves. The patient was on anti-leprosy treatment for the past 1 year with no response to treatment. Examination revealed diminished reflexes in the upper limbs and preserved reflexes in the lower limbs. Skin biopsy was normal. Magnetic resonance imaging of the spine was suggestive of Arnold–Chiari malformation type I with large cervico-dorsal syrinx which was ultimately treated by the surgical management. We suggest that all cases of leprosy should include syringomyelia as a differential diagnosis so that unnecessary prolonged exposure to anti-leprosy drugs with potential side effects can be prevented.
first_indexed 2024-12-16T14:21:11Z
format Article
id doaj.art-3b782119efe149c983bcb6d593942888
institution Directory Open Access Journal
issn 2542-551X
2542-5528
language English
last_indexed 2024-12-16T14:21:11Z
publishDate 2019-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Clinical Dermatology Review
spelling doaj.art-3b782119efe149c983bcb6d5939428882022-12-21T22:28:29ZengWolters Kluwer Medknow PublicationsClinical Dermatology Review2542-551X2542-55282019-01-013213613810.4103/CDR.CDR_13_19Syringomyelia diagnosed with leprosy: A case reportVijay SardanaRahi Kiran BhattiproluLeprosy has high incidence in tropical and subtropical countries. We document a case of 26-year-old female with an 18-month history of insidious onset progressive weakness and wasting of small muscles of both hands with decreased sensation distal to elbows and trophic changes without thickened nerves. The patient was on anti-leprosy treatment for the past 1 year with no response to treatment. Examination revealed diminished reflexes in the upper limbs and preserved reflexes in the lower limbs. Skin biopsy was normal. Magnetic resonance imaging of the spine was suggestive of Arnold–Chiari malformation type I with large cervico-dorsal syrinx which was ultimately treated by the surgical management. We suggest that all cases of leprosy should include syringomyelia as a differential diagnosis so that unnecessary prolonged exposure to anti-leprosy drugs with potential side effects can be prevented.http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2019;volume=3;issue=2;spage=136;epage=138;aulast=Sardanaarnold-chiari malformation type ileprosysyringomyelia
spellingShingle Vijay Sardana
Rahi Kiran Bhattiprolu
Syringomyelia diagnosed with leprosy: A case report
Clinical Dermatology Review
arnold-chiari malformation type i
leprosy
syringomyelia
title Syringomyelia diagnosed with leprosy: A case report
title_full Syringomyelia diagnosed with leprosy: A case report
title_fullStr Syringomyelia diagnosed with leprosy: A case report
title_full_unstemmed Syringomyelia diagnosed with leprosy: A case report
title_short Syringomyelia diagnosed with leprosy: A case report
title_sort syringomyelia diagnosed with leprosy a case report
topic arnold-chiari malformation type i
leprosy
syringomyelia
url http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2019;volume=3;issue=2;spage=136;epage=138;aulast=Sardana
work_keys_str_mv AT vijaysardana syringomyeliadiagnosedwithleprosyacasereport
AT rahikiranbhattiprolu syringomyeliadiagnosedwithleprosyacasereport