Systemic Lidocaine Infusions for Pediatric Patients with Cancer-Related Pain

Pediatric patients with cancer experience significant distress from both treatment and cancer-related pain. Careful selection of an analgesic regimen should be based upon individual patient factors, including the level of pain, response to therapy, and physiologic profile. Refractory pain is a thera...

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Main Authors: Emily Rav, Rachna Sheth, Ali H. Ahmad
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Children
Subjects:
Online Access:https://www.mdpi.com/2227-9067/9/12/1934
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author Emily Rav
Rachna Sheth
Ali H. Ahmad
author_facet Emily Rav
Rachna Sheth
Ali H. Ahmad
author_sort Emily Rav
collection DOAJ
description Pediatric patients with cancer experience significant distress from both treatment and cancer-related pain. Careful selection of an analgesic regimen should be based upon individual patient factors, including the level of pain, response to therapy, and physiologic profile. Refractory pain is a therapeutic dilemma frequently encountered in the pediatric cancer setting. Systemic lidocaine infusions have been described as both safe and efficacious, as prior studies show patients reporting decreased pain scores and improved quality of life after lidocaine treatment. Given the favorable side effect profile of lidocaine, it has the potential to be considered for analgesia in the setting of refractory pain. This review discusses the use of systemic lidocaine infusions for analgesia in pediatric oncology patients with cancer-related pain.
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spelling doaj.art-3b79f41ffa86489da3c5849d392ce1e22023-11-24T14:02:15ZengMDPI AGChildren2227-90672022-12-01912193410.3390/children9121934Systemic Lidocaine Infusions for Pediatric Patients with Cancer-Related PainEmily Rav0Rachna Sheth1Ali H. Ahmad2Pediatric Oncology Fellowship Program, Department of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USADepartment of Pediatrics-Patient Care, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USASection of Pediatric Critical Care, Department of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAPediatric patients with cancer experience significant distress from both treatment and cancer-related pain. Careful selection of an analgesic regimen should be based upon individual patient factors, including the level of pain, response to therapy, and physiologic profile. Refractory pain is a therapeutic dilemma frequently encountered in the pediatric cancer setting. Systemic lidocaine infusions have been described as both safe and efficacious, as prior studies show patients reporting decreased pain scores and improved quality of life after lidocaine treatment. Given the favorable side effect profile of lidocaine, it has the potential to be considered for analgesia in the setting of refractory pain. This review discusses the use of systemic lidocaine infusions for analgesia in pediatric oncology patients with cancer-related pain.https://www.mdpi.com/2227-9067/9/12/1934pediatricschildrencanceroncologypainlidocaine
spellingShingle Emily Rav
Rachna Sheth
Ali H. Ahmad
Systemic Lidocaine Infusions for Pediatric Patients with Cancer-Related Pain
Children
pediatrics
children
cancer
oncology
pain
lidocaine
title Systemic Lidocaine Infusions for Pediatric Patients with Cancer-Related Pain
title_full Systemic Lidocaine Infusions for Pediatric Patients with Cancer-Related Pain
title_fullStr Systemic Lidocaine Infusions for Pediatric Patients with Cancer-Related Pain
title_full_unstemmed Systemic Lidocaine Infusions for Pediatric Patients with Cancer-Related Pain
title_short Systemic Lidocaine Infusions for Pediatric Patients with Cancer-Related Pain
title_sort systemic lidocaine infusions for pediatric patients with cancer related pain
topic pediatrics
children
cancer
oncology
pain
lidocaine
url https://www.mdpi.com/2227-9067/9/12/1934
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