Biologic Graft Augmentation of Anterior Mesh Erosion Complicated by Poor Wound Healing Secondary to Heavy Tobacco Use
(1) Background: Pelvic organ prolapse (POP) is common among post-menopausal women affecting more than 25% in their lifetime—with 11% having a lifetime risk of undergoing an operation for a POP. In April 2019, the Food and Drug Administration (FDA) took surgical mesh for transvaginal use off the mark...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | Uro |
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| Online Access: | https://www.mdpi.com/2673-4397/1/3/10 |
| _version_ | 1797517029744312320 |
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| author | Cheau Williams Ethan McBrayer Samantha Leggio |
| author_facet | Cheau Williams Ethan McBrayer Samantha Leggio |
| author_sort | Cheau Williams |
| collection | DOAJ |
| description | (1) Background: Pelvic organ prolapse (POP) is common among post-menopausal women affecting more than 25% in their lifetime—with 11% having a lifetime risk of undergoing an operation for a POP. In April 2019, the Food and Drug Administration (FDA) took surgical mesh for transvaginal use off the market due to safety and effectiveness concerns. This leaves colporrhaphy or colporrhaphy with bio-graft options for a POP surgical repair. (2) Case: In this report, we look at a case with anterior mesh erosion complicated by poor wound healing secondary to heavy tobacco use and how it was successfully removed and augmented with a Coloplast axis allograft dermis biological graft secured with an Anchorsure sacrospinous ligament/arcus tendineus fascia pelvis fixation device and prolene suture. (3) Results: After failing two prior surgeries to rectify the mesh erosion, a final procedure was performed using a biologic dermal graft and a double-layer closure to aid in protecting and increasing the integrity of the tissue. (4) Conclusions: Collectively, the patient and her surgeries highlight the difficult nature of complete mesh removal and how tobacco use can significantly affect the proper healing of surgical sites. The number of surgeries necessary to address the patient’s chief complaint and the resolution of her symptoms with the biologic graft supports the challenges one faces with mesh removal and poor wound healing secondary to tobacco use. This case illustrates that complicated transvaginal mesh erosion should initially be augmented with a biologic dermal graft secured via sacrospinous ligament/arcus tendineus fascia pelvis fixation and double-layer closure and not only if visible mesh removal alone fails. |
| first_indexed | 2024-03-10T07:09:27Z |
| format | Article |
| id | doaj.art-3b7bc55ff97745ec97882754f42d1282 |
| institution | Directory Open Access Journal |
| issn | 2673-4397 |
| language | English |
| last_indexed | 2024-03-10T07:09:27Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Uro |
| spelling | doaj.art-3b7bc55ff97745ec97882754f42d12822023-11-22T15:33:36ZengMDPI AGUro2673-43972021-06-0113727510.3390/uro1030010Biologic Graft Augmentation of Anterior Mesh Erosion Complicated by Poor Wound Healing Secondary to Heavy Tobacco UseCheau Williams0Ethan McBrayer1Samantha Leggio2Colquitt Regional Medical Center, Sterling Center Urology & Urogynecology, Philadelphia College of Osteopathic Medicine, 115 31st Ave SE, Moultrie, GA 31768, USAColquitt Regional Medical Center, Georgia South Family Medicine Residency, Moultrie, GA 31768, USAPhiladelphia College of Osteopathic Medicine, Georgia Campus, Suwanee, GA 30024, USA(1) Background: Pelvic organ prolapse (POP) is common among post-menopausal women affecting more than 25% in their lifetime—with 11% having a lifetime risk of undergoing an operation for a POP. In April 2019, the Food and Drug Administration (FDA) took surgical mesh for transvaginal use off the market due to safety and effectiveness concerns. This leaves colporrhaphy or colporrhaphy with bio-graft options for a POP surgical repair. (2) Case: In this report, we look at a case with anterior mesh erosion complicated by poor wound healing secondary to heavy tobacco use and how it was successfully removed and augmented with a Coloplast axis allograft dermis biological graft secured with an Anchorsure sacrospinous ligament/arcus tendineus fascia pelvis fixation device and prolene suture. (3) Results: After failing two prior surgeries to rectify the mesh erosion, a final procedure was performed using a biologic dermal graft and a double-layer closure to aid in protecting and increasing the integrity of the tissue. (4) Conclusions: Collectively, the patient and her surgeries highlight the difficult nature of complete mesh removal and how tobacco use can significantly affect the proper healing of surgical sites. The number of surgeries necessary to address the patient’s chief complaint and the resolution of her symptoms with the biologic graft supports the challenges one faces with mesh removal and poor wound healing secondary to tobacco use. This case illustrates that complicated transvaginal mesh erosion should initially be augmented with a biologic dermal graft secured via sacrospinous ligament/arcus tendineus fascia pelvis fixation and double-layer closure and not only if visible mesh removal alone fails.https://www.mdpi.com/2673-4397/1/3/10synthetic mesh with erosionbiologic graftpelvic organ prolapsedelayed wound healing secondary to tobacco usepoor wound healingheavy tobacco use |
| spellingShingle | Cheau Williams Ethan McBrayer Samantha Leggio Biologic Graft Augmentation of Anterior Mesh Erosion Complicated by Poor Wound Healing Secondary to Heavy Tobacco Use Uro synthetic mesh with erosion biologic graft pelvic organ prolapse delayed wound healing secondary to tobacco use poor wound healing heavy tobacco use |
| title | Biologic Graft Augmentation of Anterior Mesh Erosion Complicated by Poor Wound Healing Secondary to Heavy Tobacco Use |
| title_full | Biologic Graft Augmentation of Anterior Mesh Erosion Complicated by Poor Wound Healing Secondary to Heavy Tobacco Use |
| title_fullStr | Biologic Graft Augmentation of Anterior Mesh Erosion Complicated by Poor Wound Healing Secondary to Heavy Tobacco Use |
| title_full_unstemmed | Biologic Graft Augmentation of Anterior Mesh Erosion Complicated by Poor Wound Healing Secondary to Heavy Tobacco Use |
| title_short | Biologic Graft Augmentation of Anterior Mesh Erosion Complicated by Poor Wound Healing Secondary to Heavy Tobacco Use |
| title_sort | biologic graft augmentation of anterior mesh erosion complicated by poor wound healing secondary to heavy tobacco use |
| topic | synthetic mesh with erosion biologic graft pelvic organ prolapse delayed wound healing secondary to tobacco use poor wound healing heavy tobacco use |
| url | https://www.mdpi.com/2673-4397/1/3/10 |
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