Laparoscopic retroperitoneal resection of the duodenal gastrointestinal stromal tumors in neurofibromatosis type 1; Case Report and literature review
BackgroundNeurofibromatosis type 1, also known as NF1, is a disorder that is passed down in an autosomal dominant manner. It manifests in a wide variety of tumors and affects several organ systems. It is expected that those carrying the NF1 gene will develop a rare mesenchymal tumor known as a gastr...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2022.939705/full |
| _version_ | 1818512930376777728 |
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| author | Al-Danakh Abdullah Safi Mohammed Mohammed Alradhi Xinqing Zhu Deyong Yang Deyong Yang |
| author_facet | Al-Danakh Abdullah Safi Mohammed Mohammed Alradhi Xinqing Zhu Deyong Yang Deyong Yang |
| author_sort | Al-Danakh Abdullah |
| collection | DOAJ |
| description | BackgroundNeurofibromatosis type 1, also known as NF1, is a disorder that is passed down in an autosomal dominant manner. It manifests in a wide variety of tumors and affects several organ systems. It is expected that those carrying the NF1 gene will develop a rare mesenchymal tumor known as a gastrointestinal stromal tumor (GIST) more than general population.Case reportThis research discusses a 42-year-old female patient with NF1 who was identified with a duodenal GIST but clinically and radiographically misinterpreted as having a retroperitoneal neurofibroma. She had minimally invasive retroperitoneal laparoscopic surgery to remove the tumor and primary anastomosis of the affected duodenal wall. A spindle cell GIST was entirely excised during surgery, as indicated by the pathologist. As a consequence of dialogue at a multidisciplinary team meeting, the patient was discharged from the hospital on the fourth postoperative day and is presently undergoing regular clinical follow-up.ConclusionAnatomically problematic sites, such as the duodenal GIST in NF1 patients, can be treated safely with the laparoscopic retroperitoneal approach even when retroperitoneal neoplasia arises from the intrabdominal structure and protrudes into the retroperitoneal region. |
| first_indexed | 2024-12-10T23:53:51Z |
| format | Article |
| id | doaj.art-3b7e9b23a05f4a929c14f92bef61eada |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-12-10T23:53:51Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-3b7e9b23a05f4a929c14f92bef61eada2022-12-22T01:28:39ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2022-08-01910.3389/fsurg.2022.939705939705Laparoscopic retroperitoneal resection of the duodenal gastrointestinal stromal tumors in neurofibromatosis type 1; Case Report and literature reviewAl-Danakh Abdullah0Safi Mohammed1Mohammed Alradhi2Xinqing Zhu3Deyong Yang4Deyong Yang5Department of Urology, First Affiliated Hospital of Dalian Medical University, Dalian, ChinaDepartment of Respiratory Diseases, Shandong Second Provincial General Hospital, Shandong University, Jinan, ChinaDepartment of Urology, The Affiliated Hospital of Qingdao Binhai Univesity, Qingdao, ChinaDepartment of Urology, First Affiliated Hospital of Dalian Medical University, Dalian, ChinaDepartment of Urology, First Affiliated Hospital of Dalian Medical University, Dalian, ChinaDepartment of Surgery, Healing Hands Clinic, Dalian, ChinaBackgroundNeurofibromatosis type 1, also known as NF1, is a disorder that is passed down in an autosomal dominant manner. It manifests in a wide variety of tumors and affects several organ systems. It is expected that those carrying the NF1 gene will develop a rare mesenchymal tumor known as a gastrointestinal stromal tumor (GIST) more than general population.Case reportThis research discusses a 42-year-old female patient with NF1 who was identified with a duodenal GIST but clinically and radiographically misinterpreted as having a retroperitoneal neurofibroma. She had minimally invasive retroperitoneal laparoscopic surgery to remove the tumor and primary anastomosis of the affected duodenal wall. A spindle cell GIST was entirely excised during surgery, as indicated by the pathologist. As a consequence of dialogue at a multidisciplinary team meeting, the patient was discharged from the hospital on the fourth postoperative day and is presently undergoing regular clinical follow-up.ConclusionAnatomically problematic sites, such as the duodenal GIST in NF1 patients, can be treated safely with the laparoscopic retroperitoneal approach even when retroperitoneal neoplasia arises from the intrabdominal structure and protrudes into the retroperitoneal region.https://www.frontiersin.org/articles/10.3389/fsurg.2022.939705/fullneurofibromatosisgastrointestinal stromal tumorsretroperitoneal tumorretroperitoneal approachlaparoscopic resection |
| spellingShingle | Al-Danakh Abdullah Safi Mohammed Mohammed Alradhi Xinqing Zhu Deyong Yang Deyong Yang Laparoscopic retroperitoneal resection of the duodenal gastrointestinal stromal tumors in neurofibromatosis type 1; Case Report and literature review Frontiers in Surgery neurofibromatosis gastrointestinal stromal tumors retroperitoneal tumor retroperitoneal approach laparoscopic resection |
| title | Laparoscopic retroperitoneal resection of the duodenal gastrointestinal stromal tumors in neurofibromatosis type 1; Case Report and literature review |
| title_full | Laparoscopic retroperitoneal resection of the duodenal gastrointestinal stromal tumors in neurofibromatosis type 1; Case Report and literature review |
| title_fullStr | Laparoscopic retroperitoneal resection of the duodenal gastrointestinal stromal tumors in neurofibromatosis type 1; Case Report and literature review |
| title_full_unstemmed | Laparoscopic retroperitoneal resection of the duodenal gastrointestinal stromal tumors in neurofibromatosis type 1; Case Report and literature review |
| title_short | Laparoscopic retroperitoneal resection of the duodenal gastrointestinal stromal tumors in neurofibromatosis type 1; Case Report and literature review |
| title_sort | laparoscopic retroperitoneal resection of the duodenal gastrointestinal stromal tumors in neurofibromatosis type 1 case report and literature review |
| topic | neurofibromatosis gastrointestinal stromal tumors retroperitoneal tumor retroperitoneal approach laparoscopic resection |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2022.939705/full |
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