Research Models to Study Ferroptosis’s Impact in Neurodegenerative Diseases

Research Models to Study Ferroptosis’s Impact in Neurodegenerative Diseases

Ferroptosis is a type of regulated cell death promoted by the appearance of oxidative perturbations in the intracellular microenvironment constitutively controlled by glutathione peroxidase 4 (GPX4). It is characterized by increased production of reactive oxygen species, intracellular iron accumulat...

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Bibliographic Details
Main Authors: Inês Costa, Daniel José Barbosa, Vera Silva, Sofia Benfeito, Fernanda Borges, Fernando Remião, Renata Silva
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Pharmaceutics
Subjects:
ferroptosis
in vitro models
in vivo models
neurodegenerative diseases
neurodegeneration
Online Access:https://www.mdpi.com/1999-4923/15/5/1369

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