Racial and Ethnic Minorities Have a Lower Prevalence of Airflow Obstruction than Non-Hispanic Whites
Racial and ethnic disparities in chronic obstructive pulmonary disease (COPD) are not well-studied. Our objective was to examine differences in limited COPD-related outcomes between three minority groups—African Americans (AAs), Hispanics, and American Indians (AIs) versus non-Hispanic Whites (NHWs)...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-12-01
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| Series: | COPD |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/15412555.2022.2029384 |
| _version_ | 1797403957582102528 |
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| author | Akshay Sood Hans Petersen Congjian Liu Orrin Myers Xin Wang Shore Bobbi A. Gore Rodrigo Vazquez-Guillamet Linda S. Cook Paula Meek Yohannes Tesfaigzi |
| author_facet | Akshay Sood Hans Petersen Congjian Liu Orrin Myers Xin Wang Shore Bobbi A. Gore Rodrigo Vazquez-Guillamet Linda S. Cook Paula Meek Yohannes Tesfaigzi |
| author_sort | Akshay Sood |
| collection | DOAJ |
| description | Racial and ethnic disparities in chronic obstructive pulmonary disease (COPD) are not well-studied. Our objective was to examine differences in limited COPD-related outcomes between three minority groups—African Americans (AAs), Hispanics, and American Indians (AIs) versus non-Hispanic Whites (NHWs), as the referent group, in separate cohorts. Separate cross-sectional evaluations were performed of three US-based cohorts of subjects at risk for COPD: COPDGene Study with 6,884 NHW and 3,416 AA smokers; Lovelace Smokers’ Cohort with 1,598 NHW and 378 Hispanic smokers; and Mining Dust Exposure in the United States Cohort with 2,115 NHW, 2,682 Hispanic, and 2,467 AI miners. Prebronchodilator spirometry tests were performed at baseline visits using standard criteria. The primary outcome was the prevalence of airflow obstruction. Secondary outcomes were self-reported physician diagnosis of COPD, chronic bronchitis, and modified Medical Research Council dyspnea score. All minority groups had a lower prevalence of airflow obstruction than NHWs (adjusted ORs varied from 0.29 in AIs to 0.85 in AAs; p < 0.01 for all analyses). AAs had a lower prevalence of chronic bronchitis than NHWs. In our study, all minority groups had a lower prevalence of airflow obstruction but a greater level of self-reported dyspnea than NHWs, and covariates did not explain this association. A better understanding of racial and ethnic differences in smoking-related and occupational airflow obstruction may improve prevention and therapeutic strategies. |
| first_indexed | 2024-03-09T02:47:10Z |
| format | Article |
| id | doaj.art-3b824d1230f84d3ca46ae34af902af5f |
| institution | Directory Open Access Journal |
| issn | 1541-2555 1541-2563 |
| language | English |
| last_indexed | 2024-03-09T02:47:10Z |
| publishDate | 2022-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | COPD |
| spelling | doaj.art-3b824d1230f84d3ca46ae34af902af5f2023-12-05T16:09:50ZengTaylor & Francis GroupCOPD1541-25551541-25632022-12-01191616810.1080/15412555.2022.20293842029384Racial and Ethnic Minorities Have a Lower Prevalence of Airflow Obstruction than Non-Hispanic WhitesAkshay Sood0Hans Petersen1Congjian Liu2Orrin Myers3Xin Wang Shore4Bobbi A. Gore5Rodrigo Vazquez-Guillamet6Linda S. Cook7Paula Meek8Yohannes Tesfaigzi9Department of Internal Medicine, University of New Mexico School of MedicineCOPD Program, Lovelace Respiratory Research InstituteDepartment of Internal Medicine, Brigham and Women’s HospitalDepartment of Family and Community Medicine, University of New Mexico School of MedicineDepartment of Family and Community Medicine, University of New Mexico School of MedicineBlack Lung Program, Miners Colfax Medical CenterDepartment of Internal Medicine, Washington University in St. LouisDepartment of Epidemiology, University of Colorado School of Public HealthPhD Program, University of Utah College of NursingCOPD Program, Lovelace Respiratory Research InstituteRacial and ethnic disparities in chronic obstructive pulmonary disease (COPD) are not well-studied. Our objective was to examine differences in limited COPD-related outcomes between three minority groups—African Americans (AAs), Hispanics, and American Indians (AIs) versus non-Hispanic Whites (NHWs), as the referent group, in separate cohorts. Separate cross-sectional evaluations were performed of three US-based cohorts of subjects at risk for COPD: COPDGene Study with 6,884 NHW and 3,416 AA smokers; Lovelace Smokers’ Cohort with 1,598 NHW and 378 Hispanic smokers; and Mining Dust Exposure in the United States Cohort with 2,115 NHW, 2,682 Hispanic, and 2,467 AI miners. Prebronchodilator spirometry tests were performed at baseline visits using standard criteria. The primary outcome was the prevalence of airflow obstruction. Secondary outcomes were self-reported physician diagnosis of COPD, chronic bronchitis, and modified Medical Research Council dyspnea score. All minority groups had a lower prevalence of airflow obstruction than NHWs (adjusted ORs varied from 0.29 in AIs to 0.85 in AAs; p < 0.01 for all analyses). AAs had a lower prevalence of chronic bronchitis than NHWs. In our study, all minority groups had a lower prevalence of airflow obstruction but a greater level of self-reported dyspnea than NHWs, and covariates did not explain this association. A better understanding of racial and ethnic differences in smoking-related and occupational airflow obstruction may improve prevention and therapeutic strategies.http://dx.doi.org/10.1080/15412555.2022.2029384copdchronic bronchitisemphysemaafrican americanshispanic americansamerican indiansminersracial and ethnic differencesspirometric diagnosis of airflow obstruction |
| spellingShingle | Akshay Sood Hans Petersen Congjian Liu Orrin Myers Xin Wang Shore Bobbi A. Gore Rodrigo Vazquez-Guillamet Linda S. Cook Paula Meek Yohannes Tesfaigzi Racial and Ethnic Minorities Have a Lower Prevalence of Airflow Obstruction than Non-Hispanic Whites COPD copd chronic bronchitis emphysema african americans hispanic americans american indians miners racial and ethnic differences spirometric diagnosis of airflow obstruction |
| title | Racial and Ethnic Minorities Have a Lower Prevalence of Airflow Obstruction than Non-Hispanic Whites |
| title_full | Racial and Ethnic Minorities Have a Lower Prevalence of Airflow Obstruction than Non-Hispanic Whites |
| title_fullStr | Racial and Ethnic Minorities Have a Lower Prevalence of Airflow Obstruction than Non-Hispanic Whites |
| title_full_unstemmed | Racial and Ethnic Minorities Have a Lower Prevalence of Airflow Obstruction than Non-Hispanic Whites |
| title_short | Racial and Ethnic Minorities Have a Lower Prevalence of Airflow Obstruction than Non-Hispanic Whites |
| title_sort | racial and ethnic minorities have a lower prevalence of airflow obstruction than non hispanic whites |
| topic | copd chronic bronchitis emphysema african americans hispanic americans american indians miners racial and ethnic differences spirometric diagnosis of airflow obstruction |
| url | http://dx.doi.org/10.1080/15412555.2022.2029384 |
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