Dual Roles of Prolactin and Vasoinhibin in Inflammatory Arthritis

Dual Roles of Prolactin and Vasoinhibin in Inflammatory Arthritis

The term inflammatory arthritis defines a family of diseases, including rheumatoid arthritis (RA), caused by an overactive immune system, and influenced by host aspects including sex, reproductive state, and stress. Prolactin (PRL) is a sexually dimorphic, reproductive, stress-related hormone long-l...

Full description

Bibliographic Details
Main Authors:	Carmen Clapp, Georgina Ortiz, Jose F. García-Rodrigo, María G. Ledesma-Colunga, Oscar F. Martínez-Díaz, Norma Adán, Gonzalo Martínez de la Escalera
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-06-01
Series:	Frontiers in Endocrinology
Subjects:	rheumatoid arthritis proinflammatory cytokines joint inflammation angiogenesis synovial fibroblasts endothelial cells
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2022.905756/full

Similar Items

Prolactin blocks the expression of receptor activator of nuclear factor κB ligand and reduces osteoclastogenesis and bone loss in murine inflammatory arthritis
by: Maria G. Ledesma-Colunga, et al.
Published: (2017-05-01)

THE IMPORTANCE OF CYTOKINES IN PERIODONTAL DISEASE AND RHEUMATOID ARTHRITIS. REVIEW
by: Maria Alexandra Martu, et al.
Published: (2019-07-01)

Impact of Δ<sup>9</sup>-Tetrahydrocannabinol on Rheumatoid Arthritis Synovial Fibroblasts Alone and in Co-Culture with Peripheral Blood Mononuclear Cells
by: Torsten Lowin, et al.
Published: (2022-05-01)

Regulation of cytokine and chemokine expression by histone lysine methyltransferase MLL1 in rheumatoid arthritis synovial fibroblasts
by: Keita Okamoto, et al.
Published: (2024-05-01)

Differential Expression Profiles of the Transcriptome and miRNA Interactome in Synovial Fibroblasts of Rheumatoid Arthritis Revealed by Next Generation Sequencing
by: Chia-Chun Tseng, et al.
Published: (2019-08-01)

Synovial Tissue Inflammation Mediated by Autoimmune T Cells
by: Yusuke Takeuchi, et al.
Published: (2019-08-01)

Enhanced angiogenic function in response to fibroblasts from psoriatic arthritis synovium compared to rheumatoid arthritis
by: S. Fromm, et al.
Published: (2019-12-01)

The morphological structure of the synovial membrane in rheumatoid arthritis
by: Komarova E.B., et al.
Published: (2013-01-01)

Defective T-Cell Apoptosis and T-Regulatory Cell Dysfunction in Rheumatoid Arthritis
by: Charles J. Malemud
Published: (2018-11-01)

TIME COURSE OF CHANGES IN THE SYNOVIAL FLUID LEVELS OF PROINFLAMMATORY CYTOKINES IN RHEUMATOID ATHRITIS PATIENTS DURING RITUXIMAB TREATMENT
by: A V Bezgin, et al.
Published: (2011-08-01)

Exploring the molecular mechanisms and shared potential drugs between rheumatoid arthritis and arthrofibrosis based on large language model and synovial microenvironment analysis
by: Zhaoquan Wei, et al.
Published: (2024-08-01)

Proinflammatory cytokines and depression in rheumatoid arthritis
by: Tatyana Andreyevna Lisitsyna, et al.
Published: (2013-06-01)

Human Prolactin Point Mutations and Their Projected Effect on Vasoinhibin Generation and Vasoinhibin-Related Diseases
by: Jakob Triebel, et al.
Published: (2017-11-01)

E2F2 directly regulates the STAT1 and PI3K/AKT/NF-κB pathways to exacerbate the inflammatory phenotype in rheumatoid arthritis synovial fibroblasts and mouse embryonic fibroblasts
by: Shiguan Wang, et al.
Published: (2018-10-01)

Correlation of myomir-206 and proinflammatory cytokines (IL-16 and IL-17) in patients with rheumatoid arthritis
by: Amira Abo ElAtta, et al.
Published: (2019-04-01)

LEVELS OF ANGIOGENESIS-REGULATORY CHEMOKINES IN THE SYNOVIAL FLUID OF PATIENTS WITH RHEUMATOID ARTHRITIS
by: D. A. Zhebrun, et al.
Published: (2015-03-01)

Hi-JAKi-ng Synovial Fibroblasts in Inflammatory Arthritis With JAK Inhibitors
by: Blaž Burja, et al.
Published: (2020-05-01)

The role of prolactin/vasoinhibins in cardiovascular diseases
by: Hui Zhao, et al.
Published: (2023-04-01)

Senescent synovial fibroblasts accumulate prematurely in rheumatoid arthritis tissues and display an enhanced inflammatory phenotype
by: Manuel J. Del Rey, et al.
Published: (2019-11-01)

Effects of tofacitinib on the clinical features of periodontitis in patients with rheumatoid arthritis: two case reports
by: Tetsuo Kobayashi, et al.
Published: (2019-04-01)

New Insights From Single-Cell Sequencing Data: Synovial Fibroblasts and Synovial Macrophages in Rheumatoid Arthritis
by: Liyun Cheng, et al.
Published: (2021-07-01)

A Dysregulation of the Prolactin/Vasoinhibin Axis Appears to Contribute to Preeclampsia
by: Livia Lenke, et al.
Published: (2020-01-01)

Components of the sympathetic nervous system as targets to modulate inflammation – rheumatoid arthritis synovial fibroblasts as neuron-like cells?
by: Xinkun Cheng, et al.
Published: (2023-03-01)

KLF9 positively regulates TRIM33 to inhibit abnormal synovial fibroblast proliferation, migration as well as inflammation in rheumatoid arthritis
by: Dan Huang, et al.
Published: (2022-11-01)

Ets-2 Propagates IL-6 Trans-Signaling Mediated Osteoclast-Like Changes in Human Rheumatoid Arthritis Synovial Fibroblast
by: Anil K. Singh, et al.
Published: (2021-11-01)

Corrigendum: Ets-2 Propagates IL-6 Trans-Signaling Mediated Osteoclast-Like Changes in Human Rheumatoid Arthritis Synovial Fibroblast
by: Anil K. Singh, et al.
Published: (2021-11-01)

Multiomics landscape of synovial fibroblasts in rheumatoid arthritis
by: Haruka Tsuchiya, et al.
Published: (2021-03-01)

Inhibition of NUCB2 suppresses the proliferation, migration, and invasion of rheumatoid arthritis synovial fibroblasts from patients with rheumatoid arthritis in vitro
by: Shuo Zhang, et al.
Published: (2022-12-01)

From Bench to Bedside: Translating the Prolactin/Vasoinhibin Axis
by: Jakob Triebel, et al.
Published: (2017-12-01)

THE PRODUCTION OF PRO- AND ANTIINFLAMMATORY CYTOKINES BY SYNOVIAL FIBROBLASTS OF PATIENTS WITH RHEUMATOID ARTHRITIS IN VITRO WHEN USING DNA METHYLATION MODULATORS - INVESTIGATIVE STUDY
by: M. A. Shnayder, et al.
Published: (2019-05-01)

Early rheumatoid arthritis is characterised by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin
by: K. Raza
Published: (2019-11-01)

Oncostatin M-driven macrophage-fibroblast circuits as a drug target in autoimmune arthritis
by: Nam Cong-Nhat Huynh, et al.
Published: (2024-07-01)

Platycodin D relieves rheumatoid arthritis by promoting apoptosis of mitochondria to inhibit activation of hedgehog pathway
by: Peiting Li, et al.
Published: (2023-12-01)

MARKERS OF SEVERE DESTRUCTION RHEUMATOID ARTHRITIS
by: E. B. Komarova
Published: (2017-12-01)

Inflammatory and angiogenic serum profile of refractory rheumatoid arthritis
by: Manon Lesturgie-Talarek, et al.
Published: (2025-02-01)

The activin-follistatin anti-inflammatory cycle is deregulated in synovial fibroblasts
by: Magnus Diller, et al.
Published: (2019-06-01)

Rapamycin suppresses rheumatoid arthritis fibroblast synovial cell proliferation and induces apoptosis via the AKT/mTORC1 pathway
by: Shengxiao Zhang, et al.
Published: (2024-09-01)

MiR-613 inhibits proliferation and invasion and induces apoptosis of rheumatoid arthritis synovial fibroblasts by direct down-regulation of DKK1
by: Liang Liu, et al.
Published: (2019-04-01)

Induction of chronic destructive arthritis in SCID mice by arthritogenic fibroblast-like synoviocytes derived from mice with antigen-induced arthritis
by: Oliver Frey, et al.
Published: (2018-11-01)

Targeting Activated Synovial Fibroblasts in Rheumatoid Arthritis by Peficitinib
by: Magnus Diller, et al.
Published: (2019-03-01)