A New Immunosuppressive Molecule Emodin Induces both CD4+FoxP3+ and CD8+CD122+ Regulatory T Cells and Suppresses Murine Allograft Rejection

A New Immunosuppressive Molecule Emodin Induces both CD4+FoxP3+ and CD8+CD122+ Regulatory T Cells and Suppresses Murine Allograft Rejection

Due to vigorous alloimmunity, an allograft is usually rejected without any conventional immunosuppressive treatment. However, continuous global immunosuppression may cause severe side effects, including tumors and infections. Mounting evidence has shown that cyclosporine (CsA), a common immunosuppre...

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Bibliographic Details
Main Authors:	Feifei Qiu, Huazhen Liu, Chun-Ling Liang, Golay D. Nie, Zhenhua Dai
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-11-01
Series:	Frontiers in Immunology
Subjects:	transplant immunology regulatory T cell T cell immunosuppression allograft rejection
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01519/full

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