Common and Specific Marks of Different Tau Strains Following Intra-Hippocampal Injection of AD, PiD, and GGT Inoculum in hTau Transgenic Mice

Common and Specific Marks of Different Tau Strains Following Intra-Hippocampal Injection of AD, PiD, and GGT Inoculum in hTau Transgenic Mice

Heterozygous hTau mice were used for the study of tau seeding. These mice express the six human tau isoforms, with a high predominance of 3Rtau over 4Rtau. The following groups were assessed: (i) non-inoculated mice aged 9 months (<i>n</i> = 4); (ii) Alzheimer’s Disease (AD)-inoculated m...

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Bibliographic Details
Main Authors: Isidro Ferrer, Pol Andrés-Benito, Margarita Carmona, José Antonio del Rio
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
tau
seeding
Alzheimer’s disease (AD)
Pick’s disease (PiD)
globular glial tauopathy (GGT)
hTau
Online Access:https://www.mdpi.com/1422-0067/23/24/15940

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