Identification of islet-enriched long non-coding RNAs contributing to β-cell failure in type 2 diabetes

Identification of islet-enriched long non-coding RNAs contributing to β-cell failure in type 2 diabetes

Objective: Non-coding RNAs constitute a major fraction of the β-cell transcriptome. While the involvement of microRNAs is well established, the contribution of long non-coding RNAs (lncRNAs) in the regulation of β-cell functions and in diabetes development remains poorly understood. The aim of this...

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Bibliographic Details
Main Authors: Anna Motterle, Sonia Gattesco, Marie-Line Peyot, Jonathan Lou S. Esguerra, Ana Gomez-Ruiz, D. Ross Laybutt, Patrick Gilon, Frédéric Burdet, Mark Ibberson, Lena Eliasson, Marc Prentki, Romano Regazzi
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Molecular Metabolism
Subjects:
Diabetes
Insulin
Pancreatic islet
Obesity
Gene expression
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877817305409

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