Performance assessment of StandardTM Q COVID-19 Ag Test in Ouagadougou, Burkina Faso
Background: Many rapid antigen kits for SARS-CoV-2 detection have been developed and the results interpreted usually within 30 minutes. Antigen tests are recommended to be used in areas where access to the PCR method is limited, as is the case in Burkina Faso. The aim of this study is to assess the...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Zagazig University, Faculty of Medicine
2023-08-01
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| Series: | Microbes and Infectious Diseases |
| Subjects: | |
| Online Access: | https://mid.journals.ekb.eg/article_296878_c817a4406060508c1ed0a4d0d7e9e010.pdf |
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| author | Abdou Zoure Henri Ouedraogo Serge Soubeiga Tegwinde Compaoré Sylvie Zida Oumarou Ouedraogo Dinanibè Kambiré Dezemon Zingue Charlemagne Dabiré Alidou KAGAMBEGA Charles Sawadogo Zakariya Yabre Tani SAGNA Lassana Sangare |
| author_facet | Abdou Zoure Henri Ouedraogo Serge Soubeiga Tegwinde Compaoré Sylvie Zida Oumarou Ouedraogo Dinanibè Kambiré Dezemon Zingue Charlemagne Dabiré Alidou KAGAMBEGA Charles Sawadogo Zakariya Yabre Tani SAGNA Lassana Sangare |
| author_sort | Abdou Zoure |
| collection | DOAJ |
| description | Background: Many rapid antigen kits for SARS-CoV-2 detection have been developed and the results interpreted usually within 30 minutes. Antigen tests are recommended to be used in areas where access to the PCR method is limited, as is the case in Burkina Faso. The aim of this study is to assess the performance of "Standard TM Q COVID-19 Ag Test " in the detection of SARS-CoV-2 antigen. Methods: The evaluation was performed using swabs samples collected between January 26 and March 31, 2021, from 201 subjects previously diagnosed by RT-PCR. The performance of the rapid test “Standard TM Q COVID-19 Ag Test was compared to the RT-PCR test “STANDARD M nCoV real-time detection kit”. Results: Of these 201 samples, 16 were positive for the COVID-19 RT-PCR, and 185 were negative. The sensitivity of the "Standard TM Q COVID-19 Ag Test" was 100% (IC95%: 34.24- 100) in symptomatic subjects with a symptom onset time of 1 to 5 days. This sensitivity decreased to 66.67% (IC95%: 20.77- 93.85) in symptomatic subjects with a symptom onset time of 1 to 7 days. The specificity, it was 95% (IC95%: 83.5-98.62) in all symptomatic subjects and 93.75% (IC95%: 79.85-98.2) in subjects whose symptoms appeared between 1 and 5 days. Conclusion: The " Standard TM Q COVID-19 Ag Test " was better in subjects with delayed symptoms up to 5 days. However, this kit was not suitable for COVID-19 detection in asymptomatic subjects. |
| first_indexed | 2024-03-12T15:14:50Z |
| format | Article |
| id | doaj.art-3b8f8545bb1048a99e18f251416a9eb9 |
| institution | Directory Open Access Journal |
| issn | 2682-4132 2682-4140 |
| language | English |
| last_indexed | 2024-03-12T15:14:50Z |
| publishDate | 2023-08-01 |
| publisher | Zagazig University, Faculty of Medicine |
| record_format | Article |
| series | Microbes and Infectious Diseases |
| spelling | doaj.art-3b8f8545bb1048a99e18f251416a9eb92023-08-11T15:20:51ZengZagazig University, Faculty of MedicineMicrobes and Infectious Diseases2682-41322682-41402023-08-014371372310.21608/mid.2023.205094.1507296878Performance assessment of StandardTM Q COVID-19 Ag Test in Ouagadougou, Burkina FasoAbdou Zoure0Henri Ouedraogo1Serge Soubeiga2Tegwinde Compaoré3Sylvie Zida4Oumarou Ouedraogo5Dinanibè Kambiré6Dezemon Zingue7Charlemagne Dabiré8Alidou KAGAMBEGA9Charles Sawadogo10Zakariya Yabre11Tani SAGNA12Lassana Sangare13Département Biomédical et Santé Publique, Institut de Recherche en Sciences de la Santé /National Centre for Scientific and Technologic Research (IRSS/CNRST), Ouagadougou, Burkina FasoDépartement Biomédical et Santé Publique, Institut de Recherche en Sciences de la Santé /National Centre for Scientific and Technologic Research (IRSS/CNRST), Ouagadougou, Burkina FasoDépartement Biomédical et Santé Publique, Institut de Recherche en Sciences de la Santé /National Centre for Scientific and Technologic Research (IRSS/CNRST), Ouagadougou, Burkina FasoDépartement Biomédical et Santé Publique, Institut de Recherche en Sciences de la Santé /National Centre for Scientific and Technologic Research (IRSS/CNRST), Ouagadougou, Burkina FasoDépartement Biomédical et Santé Publique, Institut de Recherche en Sciences de la Santé /National Centre for Scientific and Technologic Research (IRSS/CNRST), Ouagadougou, Burkina FasoDépartement Biomédical et Santé Publique, Institut de Recherche en Sciences de la Santé /National Centre for Scientific and Technologic Research (IRSS/CNRST), Ouagadougou, Burkina FasoDépartement Biomédical et Santé Publique, Institut de Recherche en Sciences de la Santé /National Centre for Scientific and Technologic Research (IRSS/CNRST), Ouagadougou, Burkina FasoInstitut National de Santé Publique (INSP), Ministère de la Santé, Ouagadougou, Burkina FasoDépartement Biomédical et Santé Publique, Institut de Recherche en Sciences de la Santé /National Centre for Scientific and Technologic Research (IRSS/CNRST), Ouagadougou, Burkina FasoDépartement Biomédical et Santé Publique, Institut de Recherche en Sciences de la Santé /National Centre for Scientific and Technologic Research (IRSS/CNRST), Ouagadougou, Burkina FasoDirection des Laboratoires de Biologie Médicale (DLBM), Ministère de la santé et de l’Hygiène publique, Ouagadougou, Burkina FasoDirection des Laboratoires de Biologie Médicale (DLBM), Ministère de la santé et de l’Hygiène publique, Ouagadougou, Burkina FasoDépartement Biomédical et Santé Publique, Institut de Recherche en Sciences de la Santé /National Centre for Scientific and Technologic Research (IRSS/CNRST), Ouagadougou, Burkina FasoUnité de Formation et de Recherche en Sciences de la Santé (UFR-SDS), Université Joseph Ki-Zerbo, Ouagadougou, Burkina FasoBackground: Many rapid antigen kits for SARS-CoV-2 detection have been developed and the results interpreted usually within 30 minutes. Antigen tests are recommended to be used in areas where access to the PCR method is limited, as is the case in Burkina Faso. The aim of this study is to assess the performance of "Standard TM Q COVID-19 Ag Test " in the detection of SARS-CoV-2 antigen. Methods: The evaluation was performed using swabs samples collected between January 26 and March 31, 2021, from 201 subjects previously diagnosed by RT-PCR. The performance of the rapid test “Standard TM Q COVID-19 Ag Test was compared to the RT-PCR test “STANDARD M nCoV real-time detection kit”. Results: Of these 201 samples, 16 were positive for the COVID-19 RT-PCR, and 185 were negative. The sensitivity of the "Standard TM Q COVID-19 Ag Test" was 100% (IC95%: 34.24- 100) in symptomatic subjects with a symptom onset time of 1 to 5 days. This sensitivity decreased to 66.67% (IC95%: 20.77- 93.85) in symptomatic subjects with a symptom onset time of 1 to 7 days. The specificity, it was 95% (IC95%: 83.5-98.62) in all symptomatic subjects and 93.75% (IC95%: 79.85-98.2) in subjects whose symptoms appeared between 1 and 5 days. Conclusion: The " Standard TM Q COVID-19 Ag Test " was better in subjects with delayed symptoms up to 5 days. However, this kit was not suitable for COVID-19 detection in asymptomatic subjects.https://mid.journals.ekb.eg/article_296878_c817a4406060508c1ed0a4d0d7e9e010.pdfcovid-19sars-cov-2diagnosisantigen testburkina faso |
| spellingShingle | Abdou Zoure Henri Ouedraogo Serge Soubeiga Tegwinde Compaoré Sylvie Zida Oumarou Ouedraogo Dinanibè Kambiré Dezemon Zingue Charlemagne Dabiré Alidou KAGAMBEGA Charles Sawadogo Zakariya Yabre Tani SAGNA Lassana Sangare Performance assessment of StandardTM Q COVID-19 Ag Test in Ouagadougou, Burkina Faso Microbes and Infectious Diseases covid-19 sars-cov-2 diagnosis antigen test burkina faso |
| title | Performance assessment of StandardTM Q COVID-19 Ag Test in Ouagadougou, Burkina Faso |
| title_full | Performance assessment of StandardTM Q COVID-19 Ag Test in Ouagadougou, Burkina Faso |
| title_fullStr | Performance assessment of StandardTM Q COVID-19 Ag Test in Ouagadougou, Burkina Faso |
| title_full_unstemmed | Performance assessment of StandardTM Q COVID-19 Ag Test in Ouagadougou, Burkina Faso |
| title_short | Performance assessment of StandardTM Q COVID-19 Ag Test in Ouagadougou, Burkina Faso |
| title_sort | performance assessment of standardtm q covid 19 ag test in ouagadougou burkina faso |
| topic | covid-19 sars-cov-2 diagnosis antigen test burkina faso |
| url | https://mid.journals.ekb.eg/article_296878_c817a4406060508c1ed0a4d0d7e9e010.pdf |
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