Construction of a recombinant adenovirus co-expressing truncated human prostate-specific membrane antigen and mouse 4-1BBL genes and its effect on dendritic cells

Construction of a recombinant adenovirus co-expressing truncated human prostate-specific membrane antigen and mouse 4-1BBL genes and its effect on dendritic cells

Our aim was to construct a recombinant adenovirus co-expressing truncated human prostate-specific membrane antigen (tPSMA) and mouse 4-1BBL genes and to determine its effect on dendritic cells (DCs) generated from bone marrow suspensions harvested from C57BL/6 mice for which the effect of 4-1BBL on...

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Bibliographic Details
Main Authors: Xiaodong Weng, Youlin Kuang, Xiuheng Liu, Zhiyuan Chen, Hengcheng Zhu, Hui Chen, Botao Jiang, Hao Shen
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2011-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Prostate cancer
PSMA
Co-stimulatory molecule
4-1BBL
Adenovirus
Dendritic cells
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000300002

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