Simple gene signature to assess murine fibroblast polarization

Simple gene signature to assess murine fibroblast polarization

Abstract We provide an original multi-stage approach identifying a gene signature to assess murine fibroblast polarization. Prototypic polarizations (inflammatory/fibrotic) were induced by seeded mouse embryonic fibroblasts (MEFs) with TNFα or TGFß1, respectively. The transcriptomic and proteomic pr...

Full description

Bibliographic Details
Main Authors: Emmanuel Ledoult, Manel Jendoubi, Aurore Collet, Thomas Guerrier, Alexis Largy, Silvia Speca, Solange Vivier, Fabrice Bray, Martin Figeac, Eric Hachulla, Myriam Labalette, Frédéric Leprêtre, Shéhérazade Sebda, Sébastien Sanges, Christian Rolando, Vincent Sobanski, Sylvain Dubucquoi, David Launay
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-15640-6

Similar Items

Similar Items