GnT1IP-L specifically inhibits MGAT1 in the Golgi via its luminal domain
Mouse GnT1IP-L, and membrane-bound GnT1IP-S (MGAT4D) expressed in cultured cells inhibit MGAT1, the N-acetylglucosaminyltransferase that initiates the synthesis of hybrid and complex N-glycans. However, it is not known where in the secretory pathway GnT1IP-L inhibits MGAT1, nor whether GnT1IP-L inhi...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-09-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/08916 |