Dexamethasone 0.4mg Sustained-Release Intracanalicular Insert in the Management of Ocular Inflammation and Pain Following Ophthalmic Surgery: Design, Development and Place in Therapy
Cassandra C Brooks, 1 Sayena Jabbehdari, 1, 2 Preeya K Gupta 1 1Department of Ophthalmology, Duke University Eye Center, Durham, NC, USA; 2Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USACorrespondence: Preeya K GuptaDepartment of Ophthalmology,...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2020-01-01
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| Series: | Clinical Ophthalmology |
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| Online Access: | https://www.dovepress.com/dexamethasone-04mg-sustained-release-intracanalicular-insert-in-the-ma-peer-reviewed-article-OPTH |
| _version_ | 1819036296016822272 |
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| author | Brooks CC Jabbehdari S Gupta PK |
| author_facet | Brooks CC Jabbehdari S Gupta PK |
| author_sort | Brooks CC |
| collection | DOAJ |
| description | Cassandra C Brooks, 1 Sayena Jabbehdari, 1, 2 Preeya K Gupta 1 1Department of Ophthalmology, Duke University Eye Center, Durham, NC, USA; 2Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USACorrespondence: Preeya K GuptaDepartment of Ophthalmology, Duke University Eye Center, 4709 Creekstone Drive, Suite 100, Durham, NC 27703, USATel +1 919 660-5234Fax +1 919 660-5070Email preeya.gupta@duke.eduAbstract: Inflammation and pain are two prevalent findings after ocular surgery. Corticosteroids are widely administrated as a core treatment to control post-surgical inflammation and pain. Improper patient adherence to post-operative eye drop regimens, limited bioavailability of topical eye drops, and the negative impact of preservatives used in many of these eye drops, has made a strong case for novel therapies in the treatment of post-operative pain and inflammation. This review of the literature will focus on the role of intracanalicular sustained-release dexamethasone (Dextenza, Ocular Therapeutix, Bedford, MA, USA) for the management of ocular inflammation and pain.Keywords: dexamethasone, sustained-release, intracanalicular, ocular inflammation, ocular pain, ophthalmic surgery |
| first_indexed | 2024-12-21T08:03:16Z |
| format | Article |
| id | doaj.art-3ba014f7096b478a85253e9232f07bfe |
| institution | Directory Open Access Journal |
| issn | 1177-5483 |
| language | English |
| last_indexed | 2024-12-21T08:03:16Z |
| publishDate | 2020-01-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Ophthalmology |
| spelling | doaj.art-3ba014f7096b478a85253e9232f07bfe2022-12-21T19:10:52ZengDove Medical PressClinical Ophthalmology1177-54832020-01-01Volume 14899451072Dexamethasone 0.4mg Sustained-Release Intracanalicular Insert in the Management of Ocular Inflammation and Pain Following Ophthalmic Surgery: Design, Development and Place in TherapyBrooks CCJabbehdari SGupta PKCassandra C Brooks, 1 Sayena Jabbehdari, 1, 2 Preeya K Gupta 1 1Department of Ophthalmology, Duke University Eye Center, Durham, NC, USA; 2Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USACorrespondence: Preeya K GuptaDepartment of Ophthalmology, Duke University Eye Center, 4709 Creekstone Drive, Suite 100, Durham, NC 27703, USATel +1 919 660-5234Fax +1 919 660-5070Email preeya.gupta@duke.eduAbstract: Inflammation and pain are two prevalent findings after ocular surgery. Corticosteroids are widely administrated as a core treatment to control post-surgical inflammation and pain. Improper patient adherence to post-operative eye drop regimens, limited bioavailability of topical eye drops, and the negative impact of preservatives used in many of these eye drops, has made a strong case for novel therapies in the treatment of post-operative pain and inflammation. This review of the literature will focus on the role of intracanalicular sustained-release dexamethasone (Dextenza, Ocular Therapeutix, Bedford, MA, USA) for the management of ocular inflammation and pain.Keywords: dexamethasone, sustained-release, intracanalicular, ocular inflammation, ocular pain, ophthalmic surgeryhttps://www.dovepress.com/dexamethasone-04mg-sustained-release-intracanalicular-insert-in-the-ma-peer-reviewed-article-OPTHdexamethasonesustained-releaseintracanalicularocular inflammationocular painophthalmic surgery |
| spellingShingle | Brooks CC Jabbehdari S Gupta PK Dexamethasone 0.4mg Sustained-Release Intracanalicular Insert in the Management of Ocular Inflammation and Pain Following Ophthalmic Surgery: Design, Development and Place in Therapy Clinical Ophthalmology dexamethasone sustained-release intracanalicular ocular inflammation ocular pain ophthalmic surgery |
| title | Dexamethasone 0.4mg Sustained-Release Intracanalicular Insert in the Management of Ocular Inflammation and Pain Following Ophthalmic Surgery: Design, Development and Place in Therapy |
| title_full | Dexamethasone 0.4mg Sustained-Release Intracanalicular Insert in the Management of Ocular Inflammation and Pain Following Ophthalmic Surgery: Design, Development and Place in Therapy |
| title_fullStr | Dexamethasone 0.4mg Sustained-Release Intracanalicular Insert in the Management of Ocular Inflammation and Pain Following Ophthalmic Surgery: Design, Development and Place in Therapy |
| title_full_unstemmed | Dexamethasone 0.4mg Sustained-Release Intracanalicular Insert in the Management of Ocular Inflammation and Pain Following Ophthalmic Surgery: Design, Development and Place in Therapy |
| title_short | Dexamethasone 0.4mg Sustained-Release Intracanalicular Insert in the Management of Ocular Inflammation and Pain Following Ophthalmic Surgery: Design, Development and Place in Therapy |
| title_sort | dexamethasone 0 4mg sustained release intracanalicular insert in the management of ocular inflammation and pain following ophthalmic surgery design development and place in therapy |
| topic | dexamethasone sustained-release intracanalicular ocular inflammation ocular pain ophthalmic surgery |
| url | https://www.dovepress.com/dexamethasone-04mg-sustained-release-intracanalicular-insert-in-the-ma-peer-reviewed-article-OPTH |
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