Efficacy of ultra-short, response-guided sofosbuvir and daclatasvir therapy for hepatitis C in a single-arm mechanistic pilot study

Efficacy of ultra-short, response-guided sofosbuvir and daclatasvir therapy for hepatitis C in a single-arm mechanistic pilot study

Background: World Health Organization has called for research into predictive factors for selecting persons who could be successfully treated with shorter durations of direct-acting antiviral (DAA) therapy for hepatitis C. We evaluated early virological response as a means of shortening treatment an...

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Main Authors: Barnaby Flower, Le Manh Hung, Leanne Mccabe, M Azim Ansari, Chau Le Ngoc, Thu Vo Thi, Hang Vu Thi Kim, Phuong Nguyen Thi Ngoc, Le Thanh Phuong, Vo Minh Quang, Thuan Dang Trong, Thao Le Thi, Tran Nguyen Bao, Cherry Kingsley, David Smith, Richard M Hoglund, Joel Tarning, Evelyne Kestelyn, Sarah L Pett, Rogier van Doorn, Jennifer Ilo Van Nuil, Hugo Turner, Guy E Thwaites, Eleanor Barnes, Motiur Rahman, Ann Sarah Walker, Jeremy N Day, Nguyen VV Chau, Graham S Cooke
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-01-01
Series:eLife
Subjects:
Hepatitis C
genotype 6
response guided therapy
sofosbuvir
daclatasvir
Online Access:https://elifesciences.org/articles/81801

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