Hepatic lipase promotes the selective uptake of high density lipoprotein-cholesteryl esters via the scavenger receptor B1

Hepatic lipase promotes the selective uptake of high density lipoprotein-cholesteryl esters via the scavenger receptor B1

Hepatic lipase (HL) plays a major role in high-density lipoprotein (HDL) metabolism both as a lipolytic enzyme and as a ligand. To investigate whether HL enhances the uptake of HDL-cholesteryl ester (CE) via the newly described scavenger receptor BI (SR-BI), we measured the effects of expressing HL...

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Bibliographic Details
Main Authors: Gilles Lambert, Michael B. Chase, Klaus Dugi, Andre Bensadoun, H. Bryan Brewer, Jr., Silvia Santamarina-Fojo
Format: Article
Language:English
Published: Elsevier 1999-07-01
Series:Journal of Lipid Research
Subjects:
SR-BI
HDL
cholesterol
HEK 293 cells
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752033491X

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