Features Discriminating COVID-19 From Community-Acquired Pneumonia in Pediatric Patients
Purpose: To discuss the different characteristics of clinical, laboratory and chest computed tomography (CT) between coronavirus disease 2019 (COVID-19) and community-acquired pneumonia (CAP) in pediatric patients.Methods: We retrospectively retrieved data of inpatients with COVID-19 from January 21...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-11-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2020.602083/full |
| _version_ | 1811295286453075968 |
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| author | Yu Guo Wei Xia Xuehua Peng Jianbo Shao |
| author_facet | Yu Guo Wei Xia Xuehua Peng Jianbo Shao |
| author_sort | Yu Guo |
| collection | DOAJ |
| description | Purpose: To discuss the different characteristics of clinical, laboratory and chest computed tomography (CT) between coronavirus disease 2019 (COVID-19) and community-acquired pneumonia (CAP) in pediatric patients.Methods: We retrospectively retrieved data of inpatients with COVID-19 from January 21st to March 14th, 2020, and CAP from November 1st, 2019 to December 31st, 2019 in Wuhan Children's Hospital. We divided CAP into mycoplasma pneumonia and other viral pneumonia. We analyzed clinical and radiological features from those patients, and compared the differences among COVID-19, mycoplasma pneumonia and other viral pneumonia.Results: Eighty COVID-19 inpatients from January 21st to March 14th, 2020, as well as 95 inpatients with mycoplasma pneumonia and 50 inpatients with other viral pneumonia from November 1st, 2019 to December 31st, 2019 were included in our study. All patients were confirmed with RT-PCR. The clinical symptoms were similar in the three groups. Except fever and cough, diarrhea (6/80, 7.5%), tachypnea (2/80, 2.5%), and fatigue (6/80, 7.5%) were less common in COVID-19 patients. Compared to mycoplasma pneumonia and other viral pneumonia inpatients, COVID-19 patients present remarkably increased alanine aminotransferase (69/80, 86.3%). The typical CT feature of COVID-19 is ground-glass opacity, and it was more common in COVID-19 patients (32/80, 40%).Conclusion: The COVID-19 shared similar onsets with CAP. Even though the ground-glass opacity and elevated level of ALT were frequent in COVID-19, the better way for treatment and management of this disease is quickly and accurately identifying the pathogen. |
| first_indexed | 2024-04-13T05:31:02Z |
| format | Article |
| id | doaj.art-3ba61f410dfc45bb91ffebfc90c0c017 |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-04-13T05:31:02Z |
| publishDate | 2020-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-3ba61f410dfc45bb91ffebfc90c0c0172022-12-22T03:00:27ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602020-11-01810.3389/fped.2020.602083602083Features Discriminating COVID-19 From Community-Acquired Pneumonia in Pediatric PatientsYu GuoWei XiaXuehua PengJianbo ShaoPurpose: To discuss the different characteristics of clinical, laboratory and chest computed tomography (CT) between coronavirus disease 2019 (COVID-19) and community-acquired pneumonia (CAP) in pediatric patients.Methods: We retrospectively retrieved data of inpatients with COVID-19 from January 21st to March 14th, 2020, and CAP from November 1st, 2019 to December 31st, 2019 in Wuhan Children's Hospital. We divided CAP into mycoplasma pneumonia and other viral pneumonia. We analyzed clinical and radiological features from those patients, and compared the differences among COVID-19, mycoplasma pneumonia and other viral pneumonia.Results: Eighty COVID-19 inpatients from January 21st to March 14th, 2020, as well as 95 inpatients with mycoplasma pneumonia and 50 inpatients with other viral pneumonia from November 1st, 2019 to December 31st, 2019 were included in our study. All patients were confirmed with RT-PCR. The clinical symptoms were similar in the three groups. Except fever and cough, diarrhea (6/80, 7.5%), tachypnea (2/80, 2.5%), and fatigue (6/80, 7.5%) were less common in COVID-19 patients. Compared to mycoplasma pneumonia and other viral pneumonia inpatients, COVID-19 patients present remarkably increased alanine aminotransferase (69/80, 86.3%). The typical CT feature of COVID-19 is ground-glass opacity, and it was more common in COVID-19 patients (32/80, 40%).Conclusion: The COVID-19 shared similar onsets with CAP. Even though the ground-glass opacity and elevated level of ALT were frequent in COVID-19, the better way for treatment and management of this disease is quickly and accurately identifying the pathogen.https://www.frontiersin.org/articles/10.3389/fped.2020.602083/fullCOVID-19childrencomputed tomographyCommunity-Acquired Pneumonia (CAP)respiratory infection |
| spellingShingle | Yu Guo Wei Xia Xuehua Peng Jianbo Shao Features Discriminating COVID-19 From Community-Acquired Pneumonia in Pediatric Patients Frontiers in Pediatrics COVID-19 children computed tomography Community-Acquired Pneumonia (CAP) respiratory infection |
| title | Features Discriminating COVID-19 From Community-Acquired Pneumonia in Pediatric Patients |
| title_full | Features Discriminating COVID-19 From Community-Acquired Pneumonia in Pediatric Patients |
| title_fullStr | Features Discriminating COVID-19 From Community-Acquired Pneumonia in Pediatric Patients |
| title_full_unstemmed | Features Discriminating COVID-19 From Community-Acquired Pneumonia in Pediatric Patients |
| title_short | Features Discriminating COVID-19 From Community-Acquired Pneumonia in Pediatric Patients |
| title_sort | features discriminating covid 19 from community acquired pneumonia in pediatric patients |
| topic | COVID-19 children computed tomography Community-Acquired Pneumonia (CAP) respiratory infection |
| url | https://www.frontiersin.org/articles/10.3389/fped.2020.602083/full |
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