Afebrile benign convulsions with or without a reversible splenial lesion in two pediatric patients with COVID-19
Abstract Background Seizures in children with coronavirus disease 2019 (COVID-19) were markedly increased during the Omicron variant surge. Most seizures occurred with fever. New-onset afebrile seizures were rarely reported; therefore, their courses are not well-known. Case presentation Two patients...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-04-01
|
| Series: | BMC Pediatrics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12887-023-04025-x |
| _version_ | 1827956575137955840 |
|---|---|
| author | Yun Young Lee Young Ok Kim |
| author_facet | Yun Young Lee Young Ok Kim |
| author_sort | Yun Young Lee |
| collection | DOAJ |
| description | Abstract Background Seizures in children with coronavirus disease 2019 (COVID-19) were markedly increased during the Omicron variant surge. Most seizures occurred with fever. New-onset afebrile seizures were rarely reported; therefore, their courses are not well-known. Case presentation Two patients (7 and 26 months of age, respectively) with COVID-19 showed recurrent afebrile seizures immediately after resolution of a fever lasting for 2–3 days. Bilateral convulsive seizures lasted for approximately 1 min/episode (6 of 7 total episodes) and occurred 3–4 times within 2–3 h. However, the patients were alert between seizures, which is in contrast to seizures occurring with encephalopathy or encephalitis. Only one episode required acute antiseizure medication. Brain magnetic resonance imaging showed a reversible splenial lesion in one patient. The serum uric acid level was slightly increased (7.8 mg/dL) in this patient. Electroencephalography findings were all normal. During the follow-up period, no seizures or developmental problems have been observed. Conclusions COVID-19-associated, afebrile benign convulsions with or without a reversible splenial lesion are similar to ‘benign convulsions with mild gastroenteritis’; therefore, continuation of antiseizure medication does not seem necessary. |
| first_indexed | 2024-04-09T15:06:07Z |
| format | Article |
| id | doaj.art-3bad7f262e76469fb3317635a0fcbbb2 |
| institution | Directory Open Access Journal |
| issn | 1471-2431 |
| language | English |
| last_indexed | 2024-04-09T15:06:07Z |
| publishDate | 2023-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pediatrics |
| spelling | doaj.art-3bad7f262e76469fb3317635a0fcbbb22023-04-30T11:28:28ZengBMCBMC Pediatrics1471-24312023-04-012311510.1186/s12887-023-04025-xAfebrile benign convulsions with or without a reversible splenial lesion in two pediatric patients with COVID-19Yun Young Lee0Young Ok Kim1Department of Radiology, Chonnam National University Children’s HospitalDepartment of Pediatrics, Chonnam National University Children’s HospitalAbstract Background Seizures in children with coronavirus disease 2019 (COVID-19) were markedly increased during the Omicron variant surge. Most seizures occurred with fever. New-onset afebrile seizures were rarely reported; therefore, their courses are not well-known. Case presentation Two patients (7 and 26 months of age, respectively) with COVID-19 showed recurrent afebrile seizures immediately after resolution of a fever lasting for 2–3 days. Bilateral convulsive seizures lasted for approximately 1 min/episode (6 of 7 total episodes) and occurred 3–4 times within 2–3 h. However, the patients were alert between seizures, which is in contrast to seizures occurring with encephalopathy or encephalitis. Only one episode required acute antiseizure medication. Brain magnetic resonance imaging showed a reversible splenial lesion in one patient. The serum uric acid level was slightly increased (7.8 mg/dL) in this patient. Electroencephalography findings were all normal. During the follow-up period, no seizures or developmental problems have been observed. Conclusions COVID-19-associated, afebrile benign convulsions with or without a reversible splenial lesion are similar to ‘benign convulsions with mild gastroenteritis’; therefore, continuation of antiseizure medication does not seem necessary.https://doi.org/10.1186/s12887-023-04025-xCOVID-19SeizuresReversible splenial lesionChildInfant |
| spellingShingle | Yun Young Lee Young Ok Kim Afebrile benign convulsions with or without a reversible splenial lesion in two pediatric patients with COVID-19 BMC Pediatrics COVID-19 Seizures Reversible splenial lesion Child Infant |
| title | Afebrile benign convulsions with or without a reversible splenial lesion in two pediatric patients with COVID-19 |
| title_full | Afebrile benign convulsions with or without a reversible splenial lesion in two pediatric patients with COVID-19 |
| title_fullStr | Afebrile benign convulsions with or without a reversible splenial lesion in two pediatric patients with COVID-19 |
| title_full_unstemmed | Afebrile benign convulsions with or without a reversible splenial lesion in two pediatric patients with COVID-19 |
| title_short | Afebrile benign convulsions with or without a reversible splenial lesion in two pediatric patients with COVID-19 |
| title_sort | afebrile benign convulsions with or without a reversible splenial lesion in two pediatric patients with covid 19 |
| topic | COVID-19 Seizures Reversible splenial lesion Child Infant |
| url | https://doi.org/10.1186/s12887-023-04025-x |
| work_keys_str_mv | AT yunyounglee afebrilebenignconvulsionswithorwithoutareversiblespleniallesionintwopediatricpatientswithcovid19 AT youngokkim afebrilebenignconvulsionswithorwithoutareversiblespleniallesionintwopediatricpatientswithcovid19 |