A new method to derive fetal heart rate from maternal abdominal electrocardiogram: monitoring fetal heart rate during cesarean section.
Monitoring of fetal heart rate (FHR) is important during labor since it is a sensitive marker to obtain significant information about fetal condition. To take immediate response during cesarean section (CS), we noninvasively derive FHR from maternal abdominal ECG.We recruited 17 pregnant women deliv...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4334537?pdf=render |
| _version_ | 1818130078877351936 |
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| author | Huei-Ming Yeh Yi-Chung Chang Chen Lin Chien-Hung Yeh Chien-Nan Lee Ming-Kwang Shyu Ming-Hui Hung Po-Ni Hsiao Yung-Hung Wang Yu-Hsin Tseng Jenho Tsao Ling-Ping Lai Lian-Yu Lin Men-Tzung Lo |
| author_facet | Huei-Ming Yeh Yi-Chung Chang Chen Lin Chien-Hung Yeh Chien-Nan Lee Ming-Kwang Shyu Ming-Hui Hung Po-Ni Hsiao Yung-Hung Wang Yu-Hsin Tseng Jenho Tsao Ling-Ping Lai Lian-Yu Lin Men-Tzung Lo |
| author_sort | Huei-Ming Yeh |
| collection | DOAJ |
| description | Monitoring of fetal heart rate (FHR) is important during labor since it is a sensitive marker to obtain significant information about fetal condition. To take immediate response during cesarean section (CS), we noninvasively derive FHR from maternal abdominal ECG.We recruited 17 pregnant women delivered by elective cesarean section, with abdominal ECG obtained before and during the entire CS. First, a QRS-template is created by averaging all the maternal ECG heart beats. Then, Hilbert transform was applied to QRS-template to generate the other basis which is orthogonal to the QRS-template. Second, maternal QRS, P and T waves were adaptively subtracted from the composited ECG. Third, Gabor transformation was applied to obtain time-frequency spectrogram of FHR. Heart rate variability (HRV) parameters including standard deviation of normal-to-normal intervals (SDNN), 0V, 1V, 2V derived from symbolic dynamics of HRV and SD1, SD2 derived from Poincareé plot. Three emphasized stages includes: (1) before anesthesia, (2) 5 minutes after anesthesia and (3) 5 minutes before CS delivery.FHRs were successfully derived from all maternal abdominal ECGs. FHR increased 5 minutes after anesthesia and 5 minutes before delivery. As for HRV parameters, SDNN increased both 5 minutes after anesthesia and 5 minutes before delivery (21.30±9.05 vs. 13.01±6.89, P < 0.001 and 22.88±12.01 vs. 13.01±6.89, P < 0.05). SD1 did not change during anesthesia, while SD2 increased significantly 5 minutes after anesthesia (27.92±12.28 vs. 16.18±10.01, P < 0.001) and both SD2 and 0V percentage increased significantly 5 minutes before delivery (30.54±15.88 vs. 16.18±10.01, P < 0.05; 0.39±0.14 vs. 0.30±0.13, P < 0.05).We developed a novel method to automatically derive FHR from maternal abdominal ECGs and proved that it is feasible during CS. |
| first_indexed | 2024-12-11T07:59:20Z |
| format | Article |
| id | doaj.art-3bb009559ad841e6be8c3ab74c6c27e9 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-11T07:59:20Z |
| publishDate | 2015-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-3bb009559ad841e6be8c3ab74c6c27e92022-12-22T01:15:10ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01102e011750910.1371/journal.pone.0117509A new method to derive fetal heart rate from maternal abdominal electrocardiogram: monitoring fetal heart rate during cesarean section.Huei-Ming YehYi-Chung ChangChen LinChien-Hung YehChien-Nan LeeMing-Kwang ShyuMing-Hui HungPo-Ni HsiaoYung-Hung WangYu-Hsin TsengJenho TsaoLing-Ping LaiLian-Yu LinMen-Tzung LoMonitoring of fetal heart rate (FHR) is important during labor since it is a sensitive marker to obtain significant information about fetal condition. To take immediate response during cesarean section (CS), we noninvasively derive FHR from maternal abdominal ECG.We recruited 17 pregnant women delivered by elective cesarean section, with abdominal ECG obtained before and during the entire CS. First, a QRS-template is created by averaging all the maternal ECG heart beats. Then, Hilbert transform was applied to QRS-template to generate the other basis which is orthogonal to the QRS-template. Second, maternal QRS, P and T waves were adaptively subtracted from the composited ECG. Third, Gabor transformation was applied to obtain time-frequency spectrogram of FHR. Heart rate variability (HRV) parameters including standard deviation of normal-to-normal intervals (SDNN), 0V, 1V, 2V derived from symbolic dynamics of HRV and SD1, SD2 derived from Poincareé plot. Three emphasized stages includes: (1) before anesthesia, (2) 5 minutes after anesthesia and (3) 5 minutes before CS delivery.FHRs were successfully derived from all maternal abdominal ECGs. FHR increased 5 minutes after anesthesia and 5 minutes before delivery. As for HRV parameters, SDNN increased both 5 minutes after anesthesia and 5 minutes before delivery (21.30±9.05 vs. 13.01±6.89, P < 0.001 and 22.88±12.01 vs. 13.01±6.89, P < 0.05). SD1 did not change during anesthesia, while SD2 increased significantly 5 minutes after anesthesia (27.92±12.28 vs. 16.18±10.01, P < 0.001) and both SD2 and 0V percentage increased significantly 5 minutes before delivery (30.54±15.88 vs. 16.18±10.01, P < 0.05; 0.39±0.14 vs. 0.30±0.13, P < 0.05).We developed a novel method to automatically derive FHR from maternal abdominal ECGs and proved that it is feasible during CS.http://europepmc.org/articles/PMC4334537?pdf=render |
| spellingShingle | Huei-Ming Yeh Yi-Chung Chang Chen Lin Chien-Hung Yeh Chien-Nan Lee Ming-Kwang Shyu Ming-Hui Hung Po-Ni Hsiao Yung-Hung Wang Yu-Hsin Tseng Jenho Tsao Ling-Ping Lai Lian-Yu Lin Men-Tzung Lo A new method to derive fetal heart rate from maternal abdominal electrocardiogram: monitoring fetal heart rate during cesarean section. PLoS ONE |
| title | A new method to derive fetal heart rate from maternal abdominal electrocardiogram: monitoring fetal heart rate during cesarean section. |
| title_full | A new method to derive fetal heart rate from maternal abdominal electrocardiogram: monitoring fetal heart rate during cesarean section. |
| title_fullStr | A new method to derive fetal heart rate from maternal abdominal electrocardiogram: monitoring fetal heart rate during cesarean section. |
| title_full_unstemmed | A new method to derive fetal heart rate from maternal abdominal electrocardiogram: monitoring fetal heart rate during cesarean section. |
| title_short | A new method to derive fetal heart rate from maternal abdominal electrocardiogram: monitoring fetal heart rate during cesarean section. |
| title_sort | new method to derive fetal heart rate from maternal abdominal electrocardiogram monitoring fetal heart rate during cesarean section |
| url | http://europepmc.org/articles/PMC4334537?pdf=render |
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