AKIR-1 regulates proteasome subcellular function in Caenorhabditis elegans

Summary: Polyubiquitinated proteins are primarily degraded by the ubiquitin-proteasome system (UPS). Proteasomes are present both in the cytoplasm and nucleus. Here, we investigated mechanisms coordinating proteasome subcellular localization and activity in a multicellular organism. We identified th...

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Váldodahkkit: Johanna Pispa, Elisa Mikkonen, Leena Arpalahti, Congyu Jin, Carmen Martínez-Fernández, Julián Cerón, Carina I. Holmberg
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Elsevier 2023-10-01
Ráidu:iScience
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Liŋkkat:http://www.sciencedirect.com/science/article/pii/S2589004223019636