Enhancement of Tetravalent Immune Responses to Highly Conserved Epitopes of a Dengue Peptide Vaccine Conjugated to Polystyrene Nanoparticles

Enhancement of Tetravalent Immune Responses to Highly Conserved Epitopes of a Dengue Peptide Vaccine Conjugated to Polystyrene Nanoparticles

Vaccination remains the major approach to the prevention of dengue. Since the only licensed live attenuated vaccine (LAV) lacked efficacy against all four serotypes, other vaccine platforms, such as synthetic peptide vaccines, should be explored. In this study, four multi-epitope peptides (P1–P4) we...

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Bibliographic Details
Main Authors: Yanqi Chan, Seyed Davoud Jazayeri, Babu Ramanathan, Chit Laa Poh
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Vaccines
Subjects:
dengue vaccine
peptide vaccine
polystyrene nanoparticles (PSNPs)
humoral immune responses
Online Access:https://www.mdpi.com/2076-393X/8/3/417

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