Evaluation of immediate and long-term results of treatment of post-radiation injuries of the rectum
Introduction. Treatment of post-radiation damage to the rectum is a complex medical problem. The search for new methods of treatment for this category of patients based on modern achievements in regenerative surgery is urgent.The aim of the study was to evaluate the immediate and long-term results o...
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| Format: | Article |
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Remedium Group LTD
2021-06-01
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| Series: | Амбулаторная хирургия |
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| Online Access: | https://www.a-surgeon.ru/jour/article/view/231 |
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| author | Z. I. Teryushkova A. V. Vazhenin V. S. Vasilyev S. A. Vasilyev V. M. Timerbulatov |
| author_facet | Z. I. Teryushkova A. V. Vazhenin V. S. Vasilyev S. A. Vasilyev V. M. Timerbulatov |
| author_sort | Z. I. Teryushkova |
| collection | DOAJ |
| description | Introduction. Treatment of post-radiation damage to the rectum is a complex medical problem. The search for new methods of treatment for this category of patients based on modern achievements in regenerative surgery is urgent.The aim of the study was to evaluate the immediate and long-term results of treatment of post-radiation lesions of the rectum using microfat grafting.Materials and methods. The study involved 66 patients — women aged 28 to 83 years inclusive with complications of radiation therapy (rectovaginal fistulas, radiation proctitis, radiation ulcers).Results and discussion. After the treatment, there is a tendency to improve the condition. So, if before the procedure the average sizes of fistulas and ulcers were 1.67 ± 0.54 cm in diameter, then after 3 months these indicators were 1.39 ± 0.54, and after 6 months — 1.1 ± 0.56 cm Complete epithelialization of the defect was observed in all patients. The period for which it was possible to achieve complete epithelialization varies from 6 months to 2 years. On average, to achieve complete epithelialization of post-radiation damage to the rectum, most patients required 3 injections of autologous adipose tissue. Also, all patients showed an improvement in elastometry indices over time. As a result of treatment, there is a tendency to improve the quality of life of patients.Conclutions. The study allows us to conclude about the effectiveness of the treatment, as well as that in the long term, the treatment will also be effective, the likelihood of relapse is minimal. |
| first_indexed | 2024-04-10T04:00:20Z |
| format | Article |
| id | doaj.art-3bb650ac34d2491f846d7436d8daef2c |
| institution | Directory Open Access Journal |
| issn | 2712-8741 2782-2591 |
| language | Russian |
| last_indexed | 2024-04-10T04:00:20Z |
| publishDate | 2021-06-01 |
| publisher | Remedium Group LTD |
| record_format | Article |
| series | Амбулаторная хирургия |
| spelling | doaj.art-3bb650ac34d2491f846d7436d8daef2c2023-03-13T07:10:18ZrusRemedium Group LTDАмбулаторная хирургия2712-87412782-25912021-06-01181829010.21518/1995-1477-2021-18-1-82-90209Evaluation of immediate and long-term results of treatment of post-radiation injuries of the rectumZ. I. Teryushkova0A. V. Vazhenin1V. S. Vasilyev2S. A. Vasilyev3V. M. Timerbulatov4Городская клиническая больница №8Южно-уральский государственный медицинский университет; Челябинский областной клинический центр онкологии и ядерной медициныЮжно-уральский государственный медицинский университетЮжно-уральский государственный медицинский университетБашкирский государственный медицинский университетIntroduction. Treatment of post-radiation damage to the rectum is a complex medical problem. The search for new methods of treatment for this category of patients based on modern achievements in regenerative surgery is urgent.The aim of the study was to evaluate the immediate and long-term results of treatment of post-radiation lesions of the rectum using microfat grafting.Materials and methods. The study involved 66 patients — women aged 28 to 83 years inclusive with complications of radiation therapy (rectovaginal fistulas, radiation proctitis, radiation ulcers).Results and discussion. After the treatment, there is a tendency to improve the condition. So, if before the procedure the average sizes of fistulas and ulcers were 1.67 ± 0.54 cm in diameter, then after 3 months these indicators were 1.39 ± 0.54, and after 6 months — 1.1 ± 0.56 cm Complete epithelialization of the defect was observed in all patients. The period for which it was possible to achieve complete epithelialization varies from 6 months to 2 years. On average, to achieve complete epithelialization of post-radiation damage to the rectum, most patients required 3 injections of autologous adipose tissue. Also, all patients showed an improvement in elastometry indices over time. As a result of treatment, there is a tendency to improve the quality of life of patients.Conclutions. The study allows us to conclude about the effectiveness of the treatment, as well as that in the long term, the treatment will also be effective, the likelihood of relapse is minimal.https://www.a-surgeon.ru/jour/article/view/231постлучевые поврежденияпрямая кишкамикроинъекционная аутотрансплантацияоценка эффективностинепосредственные результатыотдаленные результаты |
| spellingShingle | Z. I. Teryushkova A. V. Vazhenin V. S. Vasilyev S. A. Vasilyev V. M. Timerbulatov Evaluation of immediate and long-term results of treatment of post-radiation injuries of the rectum Амбулаторная хирургия постлучевые повреждения прямая кишка микроинъекционная аутотрансплантация оценка эффективности непосредственные результаты отдаленные результаты |
| title | Evaluation of immediate and long-term results of treatment of post-radiation injuries of the rectum |
| title_full | Evaluation of immediate and long-term results of treatment of post-radiation injuries of the rectum |
| title_fullStr | Evaluation of immediate and long-term results of treatment of post-radiation injuries of the rectum |
| title_full_unstemmed | Evaluation of immediate and long-term results of treatment of post-radiation injuries of the rectum |
| title_short | Evaluation of immediate and long-term results of treatment of post-radiation injuries of the rectum |
| title_sort | evaluation of immediate and long term results of treatment of post radiation injuries of the rectum |
| topic | постлучевые повреждения прямая кишка микроинъекционная аутотрансплантация оценка эффективности непосредственные результаты отдаленные результаты |
| url | https://www.a-surgeon.ru/jour/article/view/231 |
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