Biodegradable Polymers and Polymer Composites with Antibacterial Properties
Antibiotic resistance is one of the greatest threats to global health and food security today. It becomes increasingly difficult to treat infectious disorders because antibiotics, even the newest ones, are becoming less and less effective. One of the ways taken in the Global Plan of Action announced...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-04-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/24/8/7473 |
| _version_ | 1797605068080414720 |
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| author | Anna Smola-Dmochowska Kamila Lewicka Alicja Macyk Piotr Rychter Elżbieta Pamuła Piotr Dobrzyński |
| author_facet | Anna Smola-Dmochowska Kamila Lewicka Alicja Macyk Piotr Rychter Elżbieta Pamuła Piotr Dobrzyński |
| author_sort | Anna Smola-Dmochowska |
| collection | DOAJ |
| description | Antibiotic resistance is one of the greatest threats to global health and food security today. It becomes increasingly difficult to treat infectious disorders because antibiotics, even the newest ones, are becoming less and less effective. One of the ways taken in the Global Plan of Action announced at the World Health Assembly in May 2015 is to ensure the prevention and treatment of infectious diseases. In order to do so, attempts are made to develop new antimicrobial therapeutics, including biomaterials with antibacterial activity, such as polycationic polymers, polypeptides, and polymeric systems, to provide non-antibiotic therapeutic agents, such as selected biologically active nanoparticles and chemical compounds. Another key issue is preventing food from contamination by developing antibacterial packaging materials, particularly based on degradable polymers and biocomposites. This review, in a cross-sectional way, describes the most significant research activities conducted in recent years in the field of the development of polymeric materials and polymer composites with antibacterial properties. We particularly focus on natural polymers, i.e., polysaccharides and polypeptides, which present a mechanism for combating many highly pathogenic microorganisms. We also attempt to use this knowledge to obtain synthetic polymers with similar antibacterial activity. |
| first_indexed | 2024-03-11T04:55:56Z |
| format | Article |
| id | doaj.art-3bb7a23c93a646cf8e10d2a5433ca830 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-11T04:55:56Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-3bb7a23c93a646cf8e10d2a5433ca8302023-11-17T19:41:00ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-04-01248747310.3390/ijms24087473Biodegradable Polymers and Polymer Composites with Antibacterial PropertiesAnna Smola-Dmochowska0Kamila Lewicka1Alicja Macyk2Piotr Rychter3Elżbieta Pamuła4Piotr Dobrzyński5Centre of Polymer and Carbon Materials, Polish Academy of Sciences, 34 Marii Curie-Skłodowskiej Str., 41-819 Zabrze, PolandFaculty of Science and Technology, Jan Dlugosz University in Czestochowa, 13/15 Armii Krajowej Av., 42-200 Czestochowa, PolandDepartment of Biomaterials and Composites, Faculty of Materials Science and Ceramics, AGH University of Science and Technology, 30 Mickiewicza Av., 30-059 Kraków, PolandFaculty of Science and Technology, Jan Dlugosz University in Czestochowa, 13/15 Armii Krajowej Av., 42-200 Czestochowa, PolandDepartment of Biomaterials and Composites, Faculty of Materials Science and Ceramics, AGH University of Science and Technology, 30 Mickiewicza Av., 30-059 Kraków, PolandCentre of Polymer and Carbon Materials, Polish Academy of Sciences, 34 Marii Curie-Skłodowskiej Str., 41-819 Zabrze, PolandAntibiotic resistance is one of the greatest threats to global health and food security today. It becomes increasingly difficult to treat infectious disorders because antibiotics, even the newest ones, are becoming less and less effective. One of the ways taken in the Global Plan of Action announced at the World Health Assembly in May 2015 is to ensure the prevention and treatment of infectious diseases. In order to do so, attempts are made to develop new antimicrobial therapeutics, including biomaterials with antibacterial activity, such as polycationic polymers, polypeptides, and polymeric systems, to provide non-antibiotic therapeutic agents, such as selected biologically active nanoparticles and chemical compounds. Another key issue is preventing food from contamination by developing antibacterial packaging materials, particularly based on degradable polymers and biocomposites. This review, in a cross-sectional way, describes the most significant research activities conducted in recent years in the field of the development of polymeric materials and polymer composites with antibacterial properties. We particularly focus on natural polymers, i.e., polysaccharides and polypeptides, which present a mechanism for combating many highly pathogenic microorganisms. We also attempt to use this knowledge to obtain synthetic polymers with similar antibacterial activity.https://www.mdpi.com/1422-0067/24/8/7473biodegradable polymersantibacterial polymerspolysaccharidespeptidesantimicrobial peptidespolycarbonates |
| spellingShingle | Anna Smola-Dmochowska Kamila Lewicka Alicja Macyk Piotr Rychter Elżbieta Pamuła Piotr Dobrzyński Biodegradable Polymers and Polymer Composites with Antibacterial Properties International Journal of Molecular Sciences biodegradable polymers antibacterial polymers polysaccharides peptides antimicrobial peptides polycarbonates |
| title | Biodegradable Polymers and Polymer Composites with Antibacterial Properties |
| title_full | Biodegradable Polymers and Polymer Composites with Antibacterial Properties |
| title_fullStr | Biodegradable Polymers and Polymer Composites with Antibacterial Properties |
| title_full_unstemmed | Biodegradable Polymers and Polymer Composites with Antibacterial Properties |
| title_short | Biodegradable Polymers and Polymer Composites with Antibacterial Properties |
| title_sort | biodegradable polymers and polymer composites with antibacterial properties |
| topic | biodegradable polymers antibacterial polymers polysaccharides peptides antimicrobial peptides polycarbonates |
| url | https://www.mdpi.com/1422-0067/24/8/7473 |
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