Extracellular Matrix Mechanical Properties and Regulation of the Intestinal Stem Cells: When Mechanics Control Fate

Extracellular Matrix Mechanical Properties and Regulation of the Intestinal Stem Cells: When Mechanics Control Fate

Intestinal stem cells (ISC) are crucial players in colon epithelium physiology. The accurate control of their auto-renewal, proliferation and differentiation capacities provides a constant flow of regeneration, maintaining the epithelial intestinal barrier integrity. Under stress conditions, colon e...

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Bibliographic Details
Main Authors: Lauriane Onfroy-Roy, Dimitri Hamel, Julie Foncy, Laurent Malaquin, Audrey Ferrand
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
colon
extracellular matrix
mechanical properties
topography
stiffness
deformability
Online Access:https://www.mdpi.com/2073-4409/9/12/2629

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