Does the side of middle cerebral artery compromise matters in the mortality after thrombolysis in ischemic stroke?

The impact of the side in middle cerebral artery (MCA) ischemic stroke is not well established. Our aim was to analyze the differences between right (RMCA) and left middle cerebral artery (LMCA) stroke in patients submitted to intravenous thrombolysis and the influence of the affected side in the pa...

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Main Authors: Renata Dal-Prá Ducci, Marcos Christiano Lange, Carla Heloísa Moro, Rodrigo Harger, Alexandre Luiz Longo, Norberto Luiz Cabral, Francisco Manoel Branco Germiniani, Edison Matos Nóvak, Viviane de Hiroki Flumignan Zétola
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO) 2015-08-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000800644&lng=en&tlng=en
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author Renata Dal-Prá Ducci
Marcos Christiano Lange
Carla Heloísa Moro
Rodrigo Harger
Alexandre Luiz Longo
Norberto Luiz Cabral
Francisco Manoel Branco Germiniani
Edison Matos Nóvak
Viviane de Hiroki Flumignan Zétola
author_facet Renata Dal-Prá Ducci
Marcos Christiano Lange
Carla Heloísa Moro
Rodrigo Harger
Alexandre Luiz Longo
Norberto Luiz Cabral
Francisco Manoel Branco Germiniani
Edison Matos Nóvak
Viviane de Hiroki Flumignan Zétola
author_sort Renata Dal-Prá Ducci
collection DOAJ
description The impact of the side in middle cerebral artery (MCA) ischemic stroke is not well established. Our aim was to analyze the differences between right (RMCA) and left middle cerebral artery (LMCA) stroke in patients submitted to intravenous thrombolysis and the influence of the affected side in the patient’s mortality after 3 months. Method Patients with MCA ischemic stroke submitted to intravenous thrombolysis from March 2010 to December 2011 at two Brazilian Stroke Centers were included. Differences between patients with RMCA and LMCA stroke were identified by univariate analysis. Results Forty-five patients with RMCA stroke and 67 with LMCA stroke were analyzed. Patients with LMCA had a higher incidence of atrial fibrillation (p = 0.031), although patients with RMCA more often had a previous ischemic stroke (p = 0.034). The mortality over 3 months was similar for either side (OR = 1.20 ;0.37 - 4.29, p = 0.772). Conclusion The side of the MCA ischemic stroke did not influence the patients mortality.
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spelling doaj.art-3bbbc4e1bf38401586e9c1aaff9e46552022-12-22T03:42:12ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42272015-08-0173864464710.1590/0004-282X20150079S0004-282X2015000800644Does the side of middle cerebral artery compromise matters in the mortality after thrombolysis in ischemic stroke?Renata Dal-Prá DucciMarcos Christiano LangeCarla Heloísa MoroRodrigo HargerAlexandre Luiz LongoNorberto Luiz CabralFrancisco Manoel Branco GerminianiEdison Matos NóvakViviane de Hiroki Flumignan ZétolaThe impact of the side in middle cerebral artery (MCA) ischemic stroke is not well established. Our aim was to analyze the differences between right (RMCA) and left middle cerebral artery (LMCA) stroke in patients submitted to intravenous thrombolysis and the influence of the affected side in the patient’s mortality after 3 months. Method Patients with MCA ischemic stroke submitted to intravenous thrombolysis from March 2010 to December 2011 at two Brazilian Stroke Centers were included. Differences between patients with RMCA and LMCA stroke were identified by univariate analysis. Results Forty-five patients with RMCA stroke and 67 with LMCA stroke were analyzed. Patients with LMCA had a higher incidence of atrial fibrillation (p = 0.031), although patients with RMCA more often had a previous ischemic stroke (p = 0.034). The mortality over 3 months was similar for either side (OR = 1.20 ;0.37 - 4.29, p = 0.772). Conclusion The side of the MCA ischemic stroke did not influence the patients mortality.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000800644&lng=en&tlng=enacidente vascular isquêmicoartéria cerebral médiaterapia trombolíticaprognósticomortalidade
spellingShingle Renata Dal-Prá Ducci
Marcos Christiano Lange
Carla Heloísa Moro
Rodrigo Harger
Alexandre Luiz Longo
Norberto Luiz Cabral
Francisco Manoel Branco Germiniani
Edison Matos Nóvak
Viviane de Hiroki Flumignan Zétola
Does the side of middle cerebral artery compromise matters in the mortality after thrombolysis in ischemic stroke?
Arquivos de Neuro-Psiquiatria
acidente vascular isquêmico
artéria cerebral média
terapia trombolítica
prognóstico
mortalidade
title Does the side of middle cerebral artery compromise matters in the mortality after thrombolysis in ischemic stroke?
title_full Does the side of middle cerebral artery compromise matters in the mortality after thrombolysis in ischemic stroke?
title_fullStr Does the side of middle cerebral artery compromise matters in the mortality after thrombolysis in ischemic stroke?
title_full_unstemmed Does the side of middle cerebral artery compromise matters in the mortality after thrombolysis in ischemic stroke?
title_short Does the side of middle cerebral artery compromise matters in the mortality after thrombolysis in ischemic stroke?
title_sort does the side of middle cerebral artery compromise matters in the mortality after thrombolysis in ischemic stroke
topic acidente vascular isquêmico
artéria cerebral média
terapia trombolítica
prognóstico
mortalidade
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015000800644&lng=en&tlng=en
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