Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson’s Disease Patients

Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson’s Disease Patients

Transcriptome analysis has identified a plethora of long non-coding RNAs (lncRNAs) expressed in the human brain and associated with neurological diseases. However, whether lncRNAs expression levels correlate with Parkinson’s disease (PD) pathogenesis remains unknown. Herein, we show that a number of...

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Bibliographic Details
Main Authors: Maximilianos Elkouris, Georgia Kouroupi, Alexios Vourvoukelis, Nikolaos Papagiannakis, Valeria Kaltezioti, Rebecca Matsas, Leonidas Stefanis, Maria Xilouri, Panagiotis K. Politis
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
long-non coding RNAs
Parkinson’s disease
alpha-synuclein
LRRK2
Substantia Nigra
exosomes
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00058/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2019.00058/full

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