STANDARD EVAR IN LARGE NECKS — IS IT A REASONABLE SOLUTION?
Introduction: Endovascular aneurysm repair (EVAR) has expanded into progressively more challenging anatomies. Proximal neck-morphology represents the major determinant of EVAR durability. Neck-diameter constitutes one of the most important anatomical neck features and influence proximal sealing ove...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | Portuguese |
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Sociedade Portuguesa de Angiologia e Cirurgia Vascular
2020-02-01
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| Series: | Angiologia e Cirurgia Vascular |
| Subjects: | |
| Online Access: | https://acvjournal.com/index.php/acv/article/view/235 |
| _version_ | 1797951920944447488 |
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| author | José Oliveira-Pinto Rita Soares Ferreira Nélson Oliveira Joel Sousa Frederico Bastos Gonçalves Adelino Leite Moreira Armando Mansilha |
| author_facet | José Oliveira-Pinto Rita Soares Ferreira Nélson Oliveira Joel Sousa Frederico Bastos Gonçalves Adelino Leite Moreira Armando Mansilha |
| author_sort | José Oliveira-Pinto |
| collection | DOAJ |
| description |
Introduction: Endovascular aneurysm repair (EVAR) has expanded into progressively more challenging anatomies. Proximal neck-morphology represents the major determinant of EVAR durability. Neck-diameter constitutes one of the most important anatomical neck features and influence proximal sealing over time.
The purpose of this study is to investigate the influence of wide proximal necks on outcome after standard EVAR.
Methods: MEDLINE databases were searched to identify publications addressing the relation between aortic neck diameter and incidence of AAA-related complications.
Results: Six studies were included in our review, addressing 6602 patients: 1616 with large necks and 4986 with small necks. Five studies, including 6446 patients, reported higher rates of type 1A endoleak in patients with large necks with hazard/ odds ratios ranging between 2.3–4.1. One study found a higher risk of post-implant rupture in patients with necks>30mm (HR: 5.1; 95% CI, 1.4–19.2). Four studies reported on the influence of wide necks on AAA-related mortality without finding any association. Reduced overall survival was seen in patients with large necks in 4 studies (long term survival ranged between 61.6 and 68% for wide neck patients and 75–90 % for small neck patients), mostly attributable to cardiovascular causes.
Conclusions: Patients with wide proximal necks are at greater risk for type 1A endoleak, post-implant rupture and overall-mor- tality. This subgroup of patients may be considered for more complex proximal seal strategies with fenestrated/branched devices or open repair, although there is no evidence of superiority of alternative strategies to standard EVAR in large necks.
This subgroup should be offered more stringent imaging follow-up and aggressive treatment of medical comorbidities.
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| first_indexed | 2024-04-10T22:38:13Z |
| format | Article |
| id | doaj.art-3bbe08fe654646858e027f2efd95b881 |
| institution | Directory Open Access Journal |
| issn | 1646-706X 2183-0096 |
| language | Portuguese |
| last_indexed | 2024-04-10T22:38:13Z |
| publishDate | 2020-02-01 |
| publisher | Sociedade Portuguesa de Angiologia e Cirurgia Vascular |
| record_format | Article |
| series | Angiologia e Cirurgia Vascular |
| spelling | doaj.art-3bbe08fe654646858e027f2efd95b8812023-01-16T09:09:11ZporSociedade Portuguesa de Angiologia e Cirurgia VascularAngiologia e Cirurgia Vascular1646-706X2183-00962020-02-0115410.48750/acv.235STANDARD EVAR IN LARGE NECKS — IS IT A REASONABLE SOLUTION?José Oliveira-Pinto0Rita Soares Ferreira1Nélson Oliveira2Joel Sousa3Frederico Bastos Gonçalves4Adelino Leite Moreira5Armando Mansilha6Departamento de Angiologia e Cirurgia Vascular do Hospital de São João, Porto, Portugal; Departamento de Cirurgia e Fisiologia da Faculdade de medicina da Universidade do Porto, Porto, Portugal; Serviço de Angiologia e Cirurgia Vascular do Hospital CUF Porto, Porto, PortugalServiço de Angiologia e Cirurgia Vascular, Hospital de Santa Marta, Centro Hospitalar de Lisboa Central, Lisboa, Portugal; NOVA Medical School, Lisboa, PortugalDepartamento de Angiologia e Cirurgia Vascular, Hospital do Divino Espírito Santo, Ponta Delgada, Açores, PortugalDepartamento de Angiologia e Cirurgia Vascular do Hospital de São João, Porto, Portugal; Departamento de Cirurgia e Fisiologia da Faculdade de medicina da Universidade do Porto, Porto, Portugal; Serviço de Angiologia e Cirurgia Vascular do Hospital CUF Porto, Porto, PortugalServiço de Angiologia e Cirurgia Vascular, Hospital de Santa Marta, Centro Hospitalar de Lisboa Central, Lisboa, Portugal; NOVA Medical School, Lisboa, PortugalDepartamento de Cirurgia e Fisiologia da Faculdade de medicina da Universidade do Porto, Porto, PortugalDepartamento de Angiologia e Cirurgia Vascular do Hospital de São João, Porto, Portugal; Departamento de Cirurgia e Fisiologia da Faculdade de medicina da Universidade do Porto, Porto, Portugal; Serviço de Angiologia e Cirurgia Vascular do Hospital CUF Porto, Porto, Portugal Introduction: Endovascular aneurysm repair (EVAR) has expanded into progressively more challenging anatomies. Proximal neck-morphology represents the major determinant of EVAR durability. Neck-diameter constitutes one of the most important anatomical neck features and influence proximal sealing over time. The purpose of this study is to investigate the influence of wide proximal necks on outcome after standard EVAR. Methods: MEDLINE databases were searched to identify publications addressing the relation between aortic neck diameter and incidence of AAA-related complications. Results: Six studies were included in our review, addressing 6602 patients: 1616 with large necks and 4986 with small necks. Five studies, including 6446 patients, reported higher rates of type 1A endoleak in patients with large necks with hazard/ odds ratios ranging between 2.3–4.1. One study found a higher risk of post-implant rupture in patients with necks>30mm (HR: 5.1; 95% CI, 1.4–19.2). Four studies reported on the influence of wide necks on AAA-related mortality without finding any association. Reduced overall survival was seen in patients with large necks in 4 studies (long term survival ranged between 61.6 and 68% for wide neck patients and 75–90 % for small neck patients), mostly attributable to cardiovascular causes. Conclusions: Patients with wide proximal necks are at greater risk for type 1A endoleak, post-implant rupture and overall-mor- tality. This subgroup of patients may be considered for more complex proximal seal strategies with fenestrated/branched devices or open repair, although there is no evidence of superiority of alternative strategies to standard EVAR in large necks. This subgroup should be offered more stringent imaging follow-up and aggressive treatment of medical comorbidities. https://acvjournal.com/index.php/acv/article/view/235Endovascular aneurysm repairNeck DiameterComplications |
| spellingShingle | José Oliveira-Pinto Rita Soares Ferreira Nélson Oliveira Joel Sousa Frederico Bastos Gonçalves Adelino Leite Moreira Armando Mansilha STANDARD EVAR IN LARGE NECKS — IS IT A REASONABLE SOLUTION? Angiologia e Cirurgia Vascular Endovascular aneurysm repair Neck Diameter Complications |
| title | STANDARD EVAR IN LARGE NECKS — IS IT A REASONABLE SOLUTION? |
| title_full | STANDARD EVAR IN LARGE NECKS — IS IT A REASONABLE SOLUTION? |
| title_fullStr | STANDARD EVAR IN LARGE NECKS — IS IT A REASONABLE SOLUTION? |
| title_full_unstemmed | STANDARD EVAR IN LARGE NECKS — IS IT A REASONABLE SOLUTION? |
| title_short | STANDARD EVAR IN LARGE NECKS — IS IT A REASONABLE SOLUTION? |
| title_sort | standard evar in large necks is it a reasonable solution |
| topic | Endovascular aneurysm repair Neck Diameter Complications |
| url | https://acvjournal.com/index.php/acv/article/view/235 |
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