Serum sodium and potassium levels in preeclampsia: A case-control study in a large tertiary hospital in Ghana
Background: Preeclampsia remains a poorly understood complication of pregnancy affecting 5–14% pregnancies worldwide. Recent studies indicate that serum electrolytes may play a role in preeclampsia since it is a vascular endothelial disorder. Aim: To compare serum sodium and potassium levels between...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2017-01-01
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| Series: | Cogent Medicine |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/2331205X.2017.1376898 |
| _version_ | 1828195466603397120 |
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| author | Ebenezer Owusu Darkwa Robert Djagbletey Charles Antwi-Boasiako George Aryee Daniel Sottie Alexander Akowuah |
| author_facet | Ebenezer Owusu Darkwa Robert Djagbletey Charles Antwi-Boasiako George Aryee Daniel Sottie Alexander Akowuah |
| author_sort | Ebenezer Owusu Darkwa |
| collection | DOAJ |
| description | Background: Preeclampsia remains a poorly understood complication of pregnancy affecting 5–14% pregnancies worldwide. Recent studies indicate that serum electrolytes may play a role in preeclampsia since it is a vascular endothelial disorder. Aim: To compare serum sodium and potassium levels between preeclamptics and normotensive pregnant women in a tertiary hospital in Ghana. Methods and materials: This was a case-control study consisting of 30 preeclamptics and 30 normotensive pregnant women recruited consecutively at their first third trimester pre-natal visit at Korle-Bu Teaching Hospital. Serum sodium and potassium were analysed using Sherwood Flame Photometer (Model 420 Sherwood Scientific Ltd, UK). Analysis was done using Statistical Package for Social Sciences (SPSS®) software version 20.0 and presented as means (standard deviation). A p-value of ≤0.05 was judged significant. Results: There was a significantly reduced (p < 0.001) serum sodium levels in preeclamptics (mean = 136.13; SD = 4.17 mmol/L) compared to normotensive pregnant women (mean = 142.17; SD = 5.66 mmol/L). There was a significantly reduced (p < 0.001) serum potassium levels in preeclamptics (mean = 3.45; SD = 0.54 mmol/L) compared to normotensive pregnant women (mean = 3.98; SD = 0.36 mmol/L). Conclusion: The reduced levels of serum sodium and potassium in preeclampsia as compared to normotensive pregnant women, suggests that changes in these electrolytes may be associated with preeclampsia. |
| first_indexed | 2024-04-12T09:44:14Z |
| format | Article |
| id | doaj.art-3bc09e603b44413b8fff03cca9f3272c |
| institution | Directory Open Access Journal |
| issn | 2331-205X |
| language | English |
| last_indexed | 2024-04-12T09:44:14Z |
| publishDate | 2017-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Cogent Medicine |
| spelling | doaj.art-3bc09e603b44413b8fff03cca9f3272c2022-12-22T03:38:00ZengTaylor & Francis GroupCogent Medicine2331-205X2017-01-014110.1080/2331205X.2017.13768981376898Serum sodium and potassium levels in preeclampsia: A case-control study in a large tertiary hospital in GhanaEbenezer Owusu Darkwa0Robert Djagbletey1Charles Antwi-Boasiako2George Aryee3Daniel Sottie4Alexander Akowuah5University of GhanaUniversity of GhanaUniversity of GhanaUniversity of GhanaKorle-Bu Teaching HospitalKorle-Bu Teaching HospitalBackground: Preeclampsia remains a poorly understood complication of pregnancy affecting 5–14% pregnancies worldwide. Recent studies indicate that serum electrolytes may play a role in preeclampsia since it is a vascular endothelial disorder. Aim: To compare serum sodium and potassium levels between preeclamptics and normotensive pregnant women in a tertiary hospital in Ghana. Methods and materials: This was a case-control study consisting of 30 preeclamptics and 30 normotensive pregnant women recruited consecutively at their first third trimester pre-natal visit at Korle-Bu Teaching Hospital. Serum sodium and potassium were analysed using Sherwood Flame Photometer (Model 420 Sherwood Scientific Ltd, UK). Analysis was done using Statistical Package for Social Sciences (SPSS®) software version 20.0 and presented as means (standard deviation). A p-value of ≤0.05 was judged significant. Results: There was a significantly reduced (p < 0.001) serum sodium levels in preeclamptics (mean = 136.13; SD = 4.17 mmol/L) compared to normotensive pregnant women (mean = 142.17; SD = 5.66 mmol/L). There was a significantly reduced (p < 0.001) serum potassium levels in preeclamptics (mean = 3.45; SD = 0.54 mmol/L) compared to normotensive pregnant women (mean = 3.98; SD = 0.36 mmol/L). Conclusion: The reduced levels of serum sodium and potassium in preeclampsia as compared to normotensive pregnant women, suggests that changes in these electrolytes may be associated with preeclampsia.http://dx.doi.org/10.1080/2331205X.2017.1376898preeclampsiapathophysiologysodiumpotassium |
| spellingShingle | Ebenezer Owusu Darkwa Robert Djagbletey Charles Antwi-Boasiako George Aryee Daniel Sottie Alexander Akowuah Serum sodium and potassium levels in preeclampsia: A case-control study in a large tertiary hospital in Ghana Cogent Medicine preeclampsia pathophysiology sodium potassium |
| title | Serum sodium and potassium levels in preeclampsia: A case-control study in a large tertiary hospital in Ghana |
| title_full | Serum sodium and potassium levels in preeclampsia: A case-control study in a large tertiary hospital in Ghana |
| title_fullStr | Serum sodium and potassium levels in preeclampsia: A case-control study in a large tertiary hospital in Ghana |
| title_full_unstemmed | Serum sodium and potassium levels in preeclampsia: A case-control study in a large tertiary hospital in Ghana |
| title_short | Serum sodium and potassium levels in preeclampsia: A case-control study in a large tertiary hospital in Ghana |
| title_sort | serum sodium and potassium levels in preeclampsia a case control study in a large tertiary hospital in ghana |
| topic | preeclampsia pathophysiology sodium potassium |
| url | http://dx.doi.org/10.1080/2331205X.2017.1376898 |
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