Mutations in the <i>A34R</i> gene increase the immunogenicity of vaccinia virus

Mutations in the <i>A34R</i> gene increase the immunogenicity of vaccinia virus

Vaccination is the most simple and reliable approach of protection to virus infections. The most effective agents are live vaccines, usually low-virulence organisms for humans and closely related to pathogenic viruses or attenuated as a result of mutations/deletions in the genome of pathogenic virus...

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Bibliographic Details
Main Authors: S. N. Shchelkunov, T. V. Bauer, S. N. Yakubitskiy, A. A. Sergeev, A. S. Kabanov, S. A. Pyankov
Format: Article
Language:English
Published: Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2021-04-01
Series:Вавиловский журнал генетики и селекции
Subjects:
vaccinia virus
target mutations
attenuation
immunogenicity
Online Access:https://vavilov.elpub.ru/jour/article/view/2971

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