Medication Non-Adherence among Patients with Chronic Diseases in Makkah Region

Background: The Makkah region is the most populated region in Saudi Arabia. Studying medication adherence levels may help to improve general health outcomes and decrease overall health care expenditures. Methods: We used the ARMS scale to assess medication adherence. Bivariable analysis of medicatio...

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Main Authors: Majed A. Algarni, Meznah S. Althobiti, Sarah A. Alghamdi, Huriyyah A. Alotaibi, Ohoud S. Almalki, Adnan Alharbi, Mohammad S. Alzahrani
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/14/10/2010
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author Majed A. Algarni
Meznah S. Althobiti
Sarah A. Alghamdi
Huriyyah A. Alotaibi
Ohoud S. Almalki
Adnan Alharbi
Mohammad S. Alzahrani
author_facet Majed A. Algarni
Meznah S. Althobiti
Sarah A. Alghamdi
Huriyyah A. Alotaibi
Ohoud S. Almalki
Adnan Alharbi
Mohammad S. Alzahrani
author_sort Majed A. Algarni
collection DOAJ
description Background: The Makkah region is the most populated region in Saudi Arabia. Studying medication adherence levels may help to improve general health outcomes and decrease overall health care expenditures. Methods: We used the ARMS scale to assess medication adherence. Bivariable analysis of medication non-adherence was performed. Simple and multiple logistic regression models were built to identify factors associated with medication non-adherence. Results: Participants from the Makkah region were more than two times more likely to be non-adherent to their medications compared to other regions (adjusted OR = 2.58, 95% CI: 1.49–4.46). Patients who dispensed their prescriptions at their own expense were two times more likely to be non-adherents (adjusted OR = 2.36, 95% CI: 1.11–4.98). Patients who had a monthly income ≤6000 SR were almost two times more likely to be non-adherents (unadjusted OR = 1.73, 95% CI: 1.05–2.84). Conclusion: Medication adherence is one of the most important factors to help managing the disease. We found that Makkah chronic patients are more likely to be non-adherent with their medications compared to other regions’ patients. Moreover, we found that lower monthly incomes and paying for medications out-of-pocket were significant predictors of medication non-adherence.
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spelling doaj.art-3bc539e12a50475faedf7d41e378ef4c2023-11-24T01:53:43ZengMDPI AGPharmaceutics1999-49232022-09-011410201010.3390/pharmaceutics14102010Medication Non-Adherence among Patients with Chronic Diseases in Makkah RegionMajed A. Algarni0Meznah S. Althobiti1Sarah A. Alghamdi2Huriyyah A. Alotaibi3Ohoud S. Almalki4Adnan Alharbi5Mohammad S. Alzahrani6Department of Clinical Pharmacy, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi ArabiaDepartment of Clinical Pharmacy, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi ArabiaDepartment of Clinical Pharmacy, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi ArabiaDepartment of Clinical Pharmacy, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi ArabiaDepartment of Clinical Pharmacy, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi ArabiaClinical Pharmacy Department, College of Pharmacy, Umm Al-Qura University, Makkah 21955, Saudi ArabiaDepartment of Clinical Pharmacy, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi ArabiaBackground: The Makkah region is the most populated region in Saudi Arabia. Studying medication adherence levels may help to improve general health outcomes and decrease overall health care expenditures. Methods: We used the ARMS scale to assess medication adherence. Bivariable analysis of medication non-adherence was performed. Simple and multiple logistic regression models were built to identify factors associated with medication non-adherence. Results: Participants from the Makkah region were more than two times more likely to be non-adherent to their medications compared to other regions (adjusted OR = 2.58, 95% CI: 1.49–4.46). Patients who dispensed their prescriptions at their own expense were two times more likely to be non-adherents (adjusted OR = 2.36, 95% CI: 1.11–4.98). Patients who had a monthly income ≤6000 SR were almost two times more likely to be non-adherents (unadjusted OR = 1.73, 95% CI: 1.05–2.84). Conclusion: Medication adherence is one of the most important factors to help managing the disease. We found that Makkah chronic patients are more likely to be non-adherent with their medications compared to other regions’ patients. Moreover, we found that lower monthly incomes and paying for medications out-of-pocket were significant predictors of medication non-adherence.https://www.mdpi.com/1999-4923/14/10/2010medication adherencechronic diseaseMakkah regionSaudi Arabia
spellingShingle Majed A. Algarni
Meznah S. Althobiti
Sarah A. Alghamdi
Huriyyah A. Alotaibi
Ohoud S. Almalki
Adnan Alharbi
Mohammad S. Alzahrani
Medication Non-Adherence among Patients with Chronic Diseases in Makkah Region
Pharmaceutics
medication adherence
chronic disease
Makkah region
Saudi Arabia
title Medication Non-Adherence among Patients with Chronic Diseases in Makkah Region
title_full Medication Non-Adherence among Patients with Chronic Diseases in Makkah Region
title_fullStr Medication Non-Adherence among Patients with Chronic Diseases in Makkah Region
title_full_unstemmed Medication Non-Adherence among Patients with Chronic Diseases in Makkah Region
title_short Medication Non-Adherence among Patients with Chronic Diseases in Makkah Region
title_sort medication non adherence among patients with chronic diseases in makkah region
topic medication adherence
chronic disease
Makkah region
Saudi Arabia
url https://www.mdpi.com/1999-4923/14/10/2010
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