Genetic diagnosis of inborn errors of immunity using clinical exome sequencing

Genetic diagnosis of inborn errors of immunity using clinical exome sequencing

Inborn errors of immunity (IEI) include a variety of heterogeneous genetic disorders in which defects in the immune system lead to an increased susceptibility to infections and other complications. Accurate, prompt diagnosis of IEI is crucial for treatment plan and prognostication. In this study, cl...

Full description

Bibliographic Details
Main Authors: Soon Sung Kwon, Youn Keong Cho, Seungmin Hahn, Jiyoung Oh, Dongju Won, Saeam Shin, Ji-Man Kang, Jong Gyun Ahn, Seung-Tae Lee, Jong Rak Choi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
inborn errors of immunity
next generation sequencing
clinical exome sequencing
genetic diagnosis
somatic variant
incidental finding
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1178582/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1178582/full

Similar Items