The burden of Parkinson’s disease in the Middle East and North Africa region, 1990–2019: results from the global burden of disease study 2019
Abstract Background Parkinson’s disease (PD) remains a common disabling progressive neurodegenerative disorder. We aimed to report the prevalence, death and disability-adjusted life-years (DALYs) attributable to PD in the Middle East and North Africa (MENA) region and its 21 countries by age, sex an...
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| Format: | Article |
| Language: | English |
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BMC
2023-01-01
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| Series: | BMC Public Health |
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| Online Access: | https://doi.org/10.1186/s12889-023-15018-x |
| _version_ | 1797945662550048768 |
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| author | Saeid Safiri Maryam Noori Seyed Aria Nejadghaderi Seyed Ehsan Mousavi Mark J. M. Sullman Mostafa Araj-Khodaei Kuljit Singh Ali-Asghar Kolahi Kurosh Gharagozli |
| author_facet | Saeid Safiri Maryam Noori Seyed Aria Nejadghaderi Seyed Ehsan Mousavi Mark J. M. Sullman Mostafa Araj-Khodaei Kuljit Singh Ali-Asghar Kolahi Kurosh Gharagozli |
| author_sort | Saeid Safiri |
| collection | DOAJ |
| description | Abstract Background Parkinson’s disease (PD) remains a common disabling progressive neurodegenerative disorder. We aimed to report the prevalence, death and disability-adjusted life-years (DALYs) attributable to PD in the Middle East and North Africa (MENA) region and its 21 countries by age, sex and socio-demographic index (SDI), between 1990 and 2019. Methods Publicly available data on the burden of PD in the MENA countries were retrieved from the Global Burden of Disease (GBD) 2019 project. The results are presented with age-standardised numbers and rates per 100,000 population, along with their corresponding 95% uncertainty intervals (UIs). Results In 2019, PD had an age-standardised point prevalence of 82.6 per 100,000 population in MENA and an age-standardised death rate of 5.3, which have increased from 1990 to 2019 by 15.4% and 2.3%, respectively. In 2019, the age-standardised DALY rate of PD was 84.4, which was 0.9% higher than in 1990. The highest and lowest age-standardised DALY rates of PD in 2019 were found in Qatar and Kuwait, respectively. Also in 2019, the highest number of prevalent cases and number of DALYs were found in the 75–79 age group for both sexes. In 2019, females in MENA had an overall higher DALY rate. Furthermore, from 1990 to 2019 the burden of PD generally decreased with increasing socio-economic development, up to an SDI of around 0.4, and then increased with higher levels of SDI. Conclusion An upward trend was observed in the point prevalence of PD over the last three decades. This highlights the need to allocate more resources for research. Furthermore, properly equipped healthcare services are needed for the increasing number of patients with PD. |
| first_indexed | 2024-04-10T20:58:39Z |
| format | Article |
| id | doaj.art-3bd1fb6a4ecb4f5cb8265ab6c4c65208 |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-04-10T20:58:39Z |
| publishDate | 2023-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj.art-3bd1fb6a4ecb4f5cb8265ab6c4c652082023-01-22T12:27:15ZengBMCBMC Public Health1471-24582023-01-0123111210.1186/s12889-023-15018-xThe burden of Parkinson’s disease in the Middle East and North Africa region, 1990–2019: results from the global burden of disease study 2019Saeid Safiri0Maryam Noori1Seyed Aria Nejadghaderi2Seyed Ehsan Mousavi3Mark J. M. Sullman4Mostafa Araj-Khodaei5Kuljit Singh6Ali-Asghar Kolahi7Kurosh Gharagozli8Neurosciences Research Center, Aging Research Institute, Tabriz University of Medical SciencesStudent Research Committee, School of Medicine, Iran University of Medical SciencesSchool of Medicine, Shahid Beheshti University of Medical SciencesStudent Research Committee, Tabriz University of Medical SciencesDepartment of Life and Health Sciences, University of NicosiaResearch Center for Integrative Medicine in Aging, Aging Research Institute, Tabriz University of Medical SciencesDepartment of Medicine, Griffith UniversitySocial Determinants of Health Research Center, Shahid Beheshti University of Medical SciencesBrain Mapping Research Center, Shahid Beheshti University of Medical SciencesAbstract Background Parkinson’s disease (PD) remains a common disabling progressive neurodegenerative disorder. We aimed to report the prevalence, death and disability-adjusted life-years (DALYs) attributable to PD in the Middle East and North Africa (MENA) region and its 21 countries by age, sex and socio-demographic index (SDI), between 1990 and 2019. Methods Publicly available data on the burden of PD in the MENA countries were retrieved from the Global Burden of Disease (GBD) 2019 project. The results are presented with age-standardised numbers and rates per 100,000 population, along with their corresponding 95% uncertainty intervals (UIs). Results In 2019, PD had an age-standardised point prevalence of 82.6 per 100,000 population in MENA and an age-standardised death rate of 5.3, which have increased from 1990 to 2019 by 15.4% and 2.3%, respectively. In 2019, the age-standardised DALY rate of PD was 84.4, which was 0.9% higher than in 1990. The highest and lowest age-standardised DALY rates of PD in 2019 were found in Qatar and Kuwait, respectively. Also in 2019, the highest number of prevalent cases and number of DALYs were found in the 75–79 age group for both sexes. In 2019, females in MENA had an overall higher DALY rate. Furthermore, from 1990 to 2019 the burden of PD generally decreased with increasing socio-economic development, up to an SDI of around 0.4, and then increased with higher levels of SDI. Conclusion An upward trend was observed in the point prevalence of PD over the last three decades. This highlights the need to allocate more resources for research. Furthermore, properly equipped healthcare services are needed for the increasing number of patients with PD.https://doi.org/10.1186/s12889-023-15018-xParkinson’s diseaseMiddle East and North AfricaEpidemiologyMortalityDisability-adjusted life-years |
| spellingShingle | Saeid Safiri Maryam Noori Seyed Aria Nejadghaderi Seyed Ehsan Mousavi Mark J. M. Sullman Mostafa Araj-Khodaei Kuljit Singh Ali-Asghar Kolahi Kurosh Gharagozli The burden of Parkinson’s disease in the Middle East and North Africa region, 1990–2019: results from the global burden of disease study 2019 BMC Public Health Parkinson’s disease Middle East and North Africa Epidemiology Mortality Disability-adjusted life-years |
| title | The burden of Parkinson’s disease in the Middle East and North Africa region, 1990–2019: results from the global burden of disease study 2019 |
| title_full | The burden of Parkinson’s disease in the Middle East and North Africa region, 1990–2019: results from the global burden of disease study 2019 |
| title_fullStr | The burden of Parkinson’s disease in the Middle East and North Africa region, 1990–2019: results from the global burden of disease study 2019 |
| title_full_unstemmed | The burden of Parkinson’s disease in the Middle East and North Africa region, 1990–2019: results from the global burden of disease study 2019 |
| title_short | The burden of Parkinson’s disease in the Middle East and North Africa region, 1990–2019: results from the global burden of disease study 2019 |
| title_sort | burden of parkinson s disease in the middle east and north africa region 1990 2019 results from the global burden of disease study 2019 |
| topic | Parkinson’s disease Middle East and North Africa Epidemiology Mortality Disability-adjusted life-years |
| url | https://doi.org/10.1186/s12889-023-15018-x |
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