VEGF-Loaded Heparinised Gelatine-Hydroxyapatite-Tricalcium Phosphate Scaffold Accelerates Bone Regeneration via Enhancing Osteogenesis-Angiogenesis Coupling

VEGF-Loaded Heparinised Gelatine-Hydroxyapatite-Tricalcium Phosphate Scaffold Accelerates Bone Regeneration via Enhancing Osteogenesis-Angiogenesis Coupling

Background: Bone tissue defect, one of the common orthopaedicdiseases, is traumatizing and affects patient’s lifestyle. Although autologous and xenograft bone transplantations are performed in bone tissue engineering, clinical development of bone transplantation is limited because ofvarious factors,...

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Bibliographic Details
Main Authors: Xu Chen, Chun-Yan Gao, Xiao-Yang Chu, Chun-Yan Zheng, Ying-Yi Luan, Xin He, Kai Yang, Dong-Liang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
heparin
VEGF
gelatine
hydroxyapatite
tricalcium phosphate
bone regeneration
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.915181/full

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