Impact of Botulinum Toxin Injections on Quality of Life of Patients with Long-Standing Peripheral Facial Palsy
(1) Background: Sequels of facial palsy lead to major psychosocial repercussions, disrupting patients’ quality of life (QoL). Botulinum toxin (BoNT) injections can permit us to treat long-standing facial palsy, improving facial symmetry and functional signs including synkinesis and contractures. (2)...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-03-01
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| Series: | Toxins |
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| Online Access: | https://www.mdpi.com/2072-6651/16/3/140 |
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| author | Jérémy Amar Frédéric Tankere Diane Picard Lauranne Alciato Fabienne Carré Claire Foirest |
| author_facet | Jérémy Amar Frédéric Tankere Diane Picard Lauranne Alciato Fabienne Carré Claire Foirest |
| author_sort | Jérémy Amar |
| collection | DOAJ |
| description | (1) Background: Sequels of facial palsy lead to major psychosocial repercussions, disrupting patients’ quality of life (QoL). Botulinum toxin (BoNT) injections can permit us to treat long-standing facial palsy, improving facial symmetry and functional signs including synkinesis and contractures. (2) Methods: The main aim of this study was to assess the evolution of the QoL for patients with long-standing facial palsy before, at 1 month, and at 4 months after BoNT injections by using three questionnaires (HFS-30, FaCE, and HAD). The other goals were to find clinical factors associated with the improvement in the QoL and to assess the HFS-30 questionnaire for patients with unilateral facial palsy (3) Results: Eighty-eight patients were included in this study. There was a statistically significant improvement in QoL at 1 month after injections, assessed using the three questionnaires. This improvement was sustained at 4 months after the injections, with a statistically significant difference for the HFS-30 and FaCE questionnaires. (4) Conclusions: This study showed that the BoNT injections lead to a significant increase in the QoL of patients with unilateral facial palsy. This improvement is sustained 4 months after the injections. |
| first_indexed | 2024-04-24T17:47:02Z |
| format | Article |
| id | doaj.art-3bd4c92b26bd49b6a4fd23f6b7431b2c |
| institution | Directory Open Access Journal |
| issn | 2072-6651 |
| language | English |
| last_indexed | 2024-04-24T17:47:02Z |
| publishDate | 2024-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxins |
| spelling | doaj.art-3bd4c92b26bd49b6a4fd23f6b7431b2c2024-03-27T14:06:23ZengMDPI AGToxins2072-66512024-03-0116314010.3390/toxins16030140Impact of Botulinum Toxin Injections on Quality of Life of Patients with Long-Standing Peripheral Facial PalsyJérémy Amar0Frédéric Tankere1Diane Picard2Lauranne Alciato3Fabienne Carré4Claire Foirest5ENT Department, Pitié Salpêtrière Hospital, Sorbonne Université, 75013 Paris, FranceENT Department, Pitié Salpêtrière Hospital, Sorbonne Université, 75013 Paris, FranceENT Department, Pitié Salpêtrière Hospital, Sorbonne Université, 75013 Paris, FranceENT Department, Pitié Salpêtrière Hospital, Sorbonne Université, 75013 Paris, FranceENT Department, Pitié Salpêtrière Hospital, Sorbonne Université, 75013 Paris, FranceENT Department, Pitié Salpêtrière Hospital, Sorbonne Université, 75013 Paris, France(1) Background: Sequels of facial palsy lead to major psychosocial repercussions, disrupting patients’ quality of life (QoL). Botulinum toxin (BoNT) injections can permit us to treat long-standing facial palsy, improving facial symmetry and functional signs including synkinesis and contractures. (2) Methods: The main aim of this study was to assess the evolution of the QoL for patients with long-standing facial palsy before, at 1 month, and at 4 months after BoNT injections by using three questionnaires (HFS-30, FaCE, and HAD). The other goals were to find clinical factors associated with the improvement in the QoL and to assess the HFS-30 questionnaire for patients with unilateral facial palsy (3) Results: Eighty-eight patients were included in this study. There was a statistically significant improvement in QoL at 1 month after injections, assessed using the three questionnaires. This improvement was sustained at 4 months after the injections, with a statistically significant difference for the HFS-30 and FaCE questionnaires. (4) Conclusions: This study showed that the BoNT injections lead to a significant increase in the QoL of patients with unilateral facial palsy. This improvement is sustained 4 months after the injections.https://www.mdpi.com/2072-6651/16/3/140long-standing facial palsybotulinum toxinquality of lifehemi-facial spasm 30HFS 30facial clinimetric evaluation (FaCE) |
| spellingShingle | Jérémy Amar Frédéric Tankere Diane Picard Lauranne Alciato Fabienne Carré Claire Foirest Impact of Botulinum Toxin Injections on Quality of Life of Patients with Long-Standing Peripheral Facial Palsy Toxins long-standing facial palsy botulinum toxin quality of life hemi-facial spasm 30 HFS 30 facial clinimetric evaluation (FaCE) |
| title | Impact of Botulinum Toxin Injections on Quality of Life of Patients with Long-Standing Peripheral Facial Palsy |
| title_full | Impact of Botulinum Toxin Injections on Quality of Life of Patients with Long-Standing Peripheral Facial Palsy |
| title_fullStr | Impact of Botulinum Toxin Injections on Quality of Life of Patients with Long-Standing Peripheral Facial Palsy |
| title_full_unstemmed | Impact of Botulinum Toxin Injections on Quality of Life of Patients with Long-Standing Peripheral Facial Palsy |
| title_short | Impact of Botulinum Toxin Injections on Quality of Life of Patients with Long-Standing Peripheral Facial Palsy |
| title_sort | impact of botulinum toxin injections on quality of life of patients with long standing peripheral facial palsy |
| topic | long-standing facial palsy botulinum toxin quality of life hemi-facial spasm 30 HFS 30 facial clinimetric evaluation (FaCE) |
| url | https://www.mdpi.com/2072-6651/16/3/140 |
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