Vitamin D Supplementation Regulates Postoperative Serum Levels of PD-L1 in Patients with Digestive Tract Cancer and Improves Survivals in the Highest Quintile of PD-L1: A Post Hoc Analysis of the AMATERASU Randomized Controlled Trial

Vitamin D Supplementation Regulates Postoperative Serum Levels of PD-L1 in Patients with Digestive Tract Cancer and Improves Survivals in the Highest Quintile of PD-L1: A Post Hoc Analysis of the AMATERASU Randomized Controlled Trial

Because vitamin D responsive elements have been found to be located in the PD-L1 gene, vitamin D supplementation was hypothesized to regulate serum PD-L1 levels and thus alter survival time of cancer patients. A post hoc analysis of the AMATERASU randomized, double-blind, placebo-controlled trial of...

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Bibliographic Details
Main Authors: Makoto Morita, Mai Okuyama, Taisuke Akutsu, Hironori Ohdaira, Yutaka Suzuki, Mitsuyoshi Urashima
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Nutrients
Subjects:
vitamin D
supplement
PD-L1
cancer
serum
soluble
Online Access:https://www.mdpi.com/2072-6643/13/6/1987

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