Analysis of a Comparability Test between LX Detergent Cleaning Solution and OC Detergent Cleaning Solution Using OC Sensor PLEDIA
This study aimed at comparing the performance of imported LX detergent cleaning solution (LX-CS) and the self-manufactured OC cleaning solution (OC-CS), based on functional and quantitative analysis. The functional analysis was carried out using apparent diffusion coefficient (ADC) values. For qu...
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| Format: | Article |
| Language: | English |
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The Korean Society for Clinical Laboratory Science
2021-03-01
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| Series: | Korean Journal of Clinical Laboratory Science |
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| Summary: | This study aimed at comparing the performance of imported LX detergent cleaning solution (LX-CS)
and the self-manufactured OC cleaning solution (OC-CS), based on functional and quantitative
analysis. The functional analysis was carried out using apparent diffusion coefficient (ADC) values.
For quantitative analysis, precision, linearity, and carry-over rates were measured with commercial
control materials according to the Clinical and Laboratory Standards Institute (CLSI) guidelines. Using
OC-Sensor PLEDIA (Eiken Chemical, Japan), the ADC value of all cuvettes satisfied the acceptance
criteria. For quantitative analysis, precision was less than 5.0% for the two products, and carry-over
rates were less than ±1.00%. The linearity slopes and r2 values were 1.0017 and 0.9982 in the
LX-CS, and 0.9924 and 0.9996 in the OC-CS, respectively. The correlation coefficient (r) was found
to be 0.9997. Also, the percent difference in correlation with 40 artificial-stool specimens was less
than 10% and the p-value was less than 0.1. The result of standard deviation ratio (D: ±1 SD ratio)
was similar for both products. In conclusion, the functional and quantitative analyses of the two
products were compared and showed similar results. In the future, the self-manufactured OC-CS
will be able to provide a much more stable and faster supply than the imported LX-CS. |
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| ISSN: | 1738-3544 2288-1662 |