Analysis of a Comparability Test between LX Detergent Cleaning Solution and OC Detergent Cleaning Solution Using OC Sensor PLEDIA
This study aimed at comparing the performance of imported LX detergent cleaning solution (LX-CS) and the self-manufactured OC cleaning solution (OC-CS), based on functional and quantitative analysis. The functional analysis was carried out using apparent diffusion coefficient (ADC) values. For qu...
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| Format: | Article |
| Language: | English |
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The Korean Society for Clinical Laboratory Science
2021-03-01
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| Series: | Korean Journal of Clinical Laboratory Science |
| Subjects: |
| _version_ | 1818666053895454720 |
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| author | Kyung Jae Cha |
| author_facet | Kyung Jae Cha |
| author_sort | Kyung Jae Cha |
| collection | DOAJ |
| description | This study aimed at comparing the performance of imported LX detergent cleaning solution (LX-CS)
and the self-manufactured OC cleaning solution (OC-CS), based on functional and quantitative
analysis. The functional analysis was carried out using apparent diffusion coefficient (ADC) values.
For quantitative analysis, precision, linearity, and carry-over rates were measured with commercial
control materials according to the Clinical and Laboratory Standards Institute (CLSI) guidelines. Using
OC-Sensor PLEDIA (Eiken Chemical, Japan), the ADC value of all cuvettes satisfied the acceptance
criteria. For quantitative analysis, precision was less than 5.0% for the two products, and carry-over
rates were less than ±1.00%. The linearity slopes and r2 values were 1.0017 and 0.9982 in the
LX-CS, and 0.9924 and 0.9996 in the OC-CS, respectively. The correlation coefficient (r) was found
to be 0.9997. Also, the percent difference in correlation with 40 artificial-stool specimens was less
than 10% and the p-value was less than 0.1. The result of standard deviation ratio (D: ±1 SD ratio)
was similar for both products. In conclusion, the functional and quantitative analyses of the two
products were compared and showed similar results. In the future, the self-manufactured OC-CS
will be able to provide a much more stable and faster supply than the imported LX-CS. |
| first_indexed | 2024-12-17T05:58:25Z |
| format | Article |
| id | doaj.art-3bd8862dd83342f9811c096f7cf240d3 |
| institution | Directory Open Access Journal |
| issn | 1738-3544 2288-1662 |
| language | English |
| last_indexed | 2024-12-17T05:58:25Z |
| publishDate | 2021-03-01 |
| publisher | The Korean Society for Clinical Laboratory Science |
| record_format | Article |
| series | Korean Journal of Clinical Laboratory Science |
| spelling | doaj.art-3bd8862dd83342f9811c096f7cf240d32022-12-21T22:00:57ZengThe Korean Society for Clinical Laboratory ScienceKorean Journal of Clinical Laboratory Science1738-35442288-16622021-03-01531193110.15324/kjcls.2021.53.1.19Analysis of a Comparability Test between LX Detergent Cleaning Solution and OC Detergent Cleaning Solution Using OC Sensor PLEDIAKyung Jae Cha0https://orcid.org/0000-0003-2708-2811Department of Field Application Scientist Team, Shinyang Chemical Co.,Ltd., Seoul, KoreaThis study aimed at comparing the performance of imported LX detergent cleaning solution (LX-CS) and the self-manufactured OC cleaning solution (OC-CS), based on functional and quantitative analysis. The functional analysis was carried out using apparent diffusion coefficient (ADC) values. For quantitative analysis, precision, linearity, and carry-over rates were measured with commercial control materials according to the Clinical and Laboratory Standards Institute (CLSI) guidelines. Using OC-Sensor PLEDIA (Eiken Chemical, Japan), the ADC value of all cuvettes satisfied the acceptance criteria. For quantitative analysis, precision was less than 5.0% for the two products, and carry-over rates were less than ±1.00%. The linearity slopes and r2 values were 1.0017 and 0.9982 in the LX-CS, and 0.9924 and 0.9996 in the OC-CS, respectively. The correlation coefficient (r) was found to be 0.9997. Also, the percent difference in correlation with 40 artificial-stool specimens was less than 10% and the p-value was less than 0.1. The result of standard deviation ratio (D: ±1 SD ratio) was similar for both products. In conclusion, the functional and quantitative analyses of the two products were compared and showed similar results. In the future, the self-manufactured OC-CS will be able to provide a much more stable and faster supply than the imported LX-CS.fecal occult blood testlx detergent cleaning solutionprecision |
| spellingShingle | Kyung Jae Cha Analysis of a Comparability Test between LX Detergent Cleaning Solution and OC Detergent Cleaning Solution Using OC Sensor PLEDIA Korean Journal of Clinical Laboratory Science fecal occult blood test lx detergent cleaning solution precision |
| title | Analysis of a Comparability Test between LX Detergent Cleaning Solution and OC Detergent Cleaning Solution Using OC Sensor PLEDIA |
| title_full | Analysis of a Comparability Test between LX Detergent Cleaning Solution and OC Detergent Cleaning Solution Using OC Sensor PLEDIA |
| title_fullStr | Analysis of a Comparability Test between LX Detergent Cleaning Solution and OC Detergent Cleaning Solution Using OC Sensor PLEDIA |
| title_full_unstemmed | Analysis of a Comparability Test between LX Detergent Cleaning Solution and OC Detergent Cleaning Solution Using OC Sensor PLEDIA |
| title_short | Analysis of a Comparability Test between LX Detergent Cleaning Solution and OC Detergent Cleaning Solution Using OC Sensor PLEDIA |
| title_sort | analysis of a comparability test between lx detergent cleaning solution and oc detergent cleaning solution using oc sensor pledia |
| topic | fecal occult blood test lx detergent cleaning solution precision |
| work_keys_str_mv | AT kyungjaecha analysisofacomparabilitytestbetweenlxdetergentcleaningsolutionandocdetergentcleaningsolutionusingocsensorpledia |