Toll-like receptor 2 signaling pathway activation contributes to a highly efficient inflammatory response in Japanese encephalitis virus-infected mouse microglial cells by proteomics

Toll-like receptor 2 signaling pathway activation contributes to a highly efficient inflammatory response in Japanese encephalitis virus-infected mouse microglial cells by proteomics

Thousands of people die each year from Japanese encephalitis (JE) caused by the Japanese encephalitis virus (JEV), probably due to exacerbation of the inflammatory response that impairs the course of the disease. Microglia are mononuclear phagocytic cells located within the parenchyma of the central...

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Bibliographic Details
Main Authors: Guanyu Zhao, Yan Gao, Jiaqi Zhang, He Zhang, Changzhan Xie, Fulong Nan, Sheng Feng, Zhuo Ha, Chenghui Li, Xiangyu Zhu, Zhuoxin Li, Ping Zhang, Ying Zhang, Huijun Lu, Ningyi Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Microbiology
Subjects:
Japanese encephalitis virus (JEV)
toll-like receptor 2 (TLR2)
proteomics
inflammatory response
microglial
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.989183/full

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