Phenotypic Resistance of Staphylococcus aureus to Antibiotics in Dogs of Tamale Metropolis, Ghana
Introduction: Staphylococcus aureus is an important bacterium which induces a wide range of diseases. Its presence in dogs and resistance to antibiotics is a threat to public health due to the close association of humans with dogs. The aim of the present study was to determine the phenotypic resist...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Rovedar
2022-09-01
|
| Series: | Small Animal Advances |
| Subjects: | |
| Online Access: | https://saa.rovedar.com/index.php/SAA/article/view/4 |
| _version_ | 1797246918893502464 |
|---|---|
| author | Frederick Adzitey Nicholas Prah Hafiz Salifu David Yidana |
| author_facet | Frederick Adzitey Nicholas Prah Hafiz Salifu David Yidana |
| author_sort | Frederick Adzitey |
| collection | DOAJ |
| description |
Introduction: Staphylococcus aureus is an important bacterium which induces a wide range of diseases. Its presence in dogs and resistance to antibiotics is a threat to public health due to the close association of humans with dogs. The aim of the present study was to determine the phenotypic resistance of Staphylococcus aureus (S. aureus) to antibiotics in dogs without any clinical manifestation of diseases in Tamale Metropolis, Ghana. The current study also examined microbial load in these dogs. Materials and methods: A total of 120 samples from various parts of dogs, including the mouth, nose, anus, inner ear, and outer ear, were examined. Isolation and antibiotic resistance of S. aureus were determined using the USA Bacteriological Analytical Manual and the Disc Diffusion method, respectively.
Results: The presence of S. aureus in the dogs ranged from 8.3% (anus) to 58.3% (nose), averaging 40%. The microbial load also ranged from 2.9 log cfu/cm2 (mouth) to 3.4 log cfu/cm2 (outer ear), with an average of 3.2 log cfu/cm2. There were significant differences among the examined samples regarding the presence of S. aureus, but not the microbial load. The overall resistance, intermediate resistance, and susceptibility of S. aureus were 46.2%, 12.9%, and 42.2%, respectively. The S. aureus was highly resistant to teicoplanin (88.0%) and susceptible to chloramphenicol (72.0%). The multiple antibiotic indexes ranged from 0 to 0.9, and 89.1% of the isolates exhibited multidrug resistance.
Conclusion: The findings of the current study revealed that healthy dogs in Tamale Metropolis, Ghana, were carriers of S. aureus as well as other bacteria, and S. aureus exhibited different resistance patterns to antibiotics.
|
| first_indexed | 2024-04-24T19:50:26Z |
| format | Article |
| id | doaj.art-3bdab9797ed14704b4991bbb6b37625f |
| institution | Directory Open Access Journal |
| issn | 2821-2363 |
| language | English |
| last_indexed | 2024-04-24T19:50:26Z |
| publishDate | 2022-09-01 |
| publisher | Rovedar |
| record_format | Article |
| series | Small Animal Advances |
| spelling | doaj.art-3bdab9797ed14704b4991bbb6b37625f2024-03-24T15:01:37ZengRovedarSmall Animal Advances2821-23632022-09-011110.58803/saa.v1i1.4Phenotypic Resistance of Staphylococcus aureus to Antibiotics in Dogs of Tamale Metropolis, GhanaFrederick Adzitey0Nicholas Prah1Hafiz Salifu2David Yidana3Department of Animal Science, Faculty of Agriculture, Food and Consumer Sciences, University for Development Studies, P. O. Box TL 1882, Nyankpala Campus, Ghana2 Department of Veterinary Science, Faculty of Agriculture, Food and Consumer Sciences, University for Development Studies, P. O. Box TL 1882, Nyankpala Campus, GhanaDepartment of Veterinary Science, Faculty of Agriculture, Food and Consumer Sciences, University for Development Studies, P. O. Box TL 1882, Nyankpala Campus, GhanaDepartment of Veterinary Science, Faculty of Agriculture, Food and Consumer Sciences, University for Development Studies, P. O. Box TL 1882, Nyankpala Campus, Ghana Introduction: Staphylococcus aureus is an important bacterium which induces a wide range of diseases. Its presence in dogs and resistance to antibiotics is a threat to public health due to the close association of humans with dogs. The aim of the present study was to determine the phenotypic resistance of Staphylococcus aureus (S. aureus) to antibiotics in dogs without any clinical manifestation of diseases in Tamale Metropolis, Ghana. The current study also examined microbial load in these dogs. Materials and methods: A total of 120 samples from various parts of dogs, including the mouth, nose, anus, inner ear, and outer ear, were examined. Isolation and antibiotic resistance of S. aureus were determined using the USA Bacteriological Analytical Manual and the Disc Diffusion method, respectively. Results: The presence of S. aureus in the dogs ranged from 8.3% (anus) to 58.3% (nose), averaging 40%. The microbial load also ranged from 2.9 log cfu/cm2 (mouth) to 3.4 log cfu/cm2 (outer ear), with an average of 3.2 log cfu/cm2. There were significant differences among the examined samples regarding the presence of S. aureus, but not the microbial load. The overall resistance, intermediate resistance, and susceptibility of S. aureus were 46.2%, 12.9%, and 42.2%, respectively. The S. aureus was highly resistant to teicoplanin (88.0%) and susceptible to chloramphenicol (72.0%). The multiple antibiotic indexes ranged from 0 to 0.9, and 89.1% of the isolates exhibited multidrug resistance. Conclusion: The findings of the current study revealed that healthy dogs in Tamale Metropolis, Ghana, were carriers of S. aureus as well as other bacteria, and S. aureus exhibited different resistance patterns to antibiotics. https://saa.rovedar.com/index.php/SAA/article/view/4Antibiotic resistanceDogsPhenotypicPublic healthStaphylococcus aureus |
| spellingShingle | Frederick Adzitey Nicholas Prah Hafiz Salifu David Yidana Phenotypic Resistance of Staphylococcus aureus to Antibiotics in Dogs of Tamale Metropolis, Ghana Small Animal Advances Antibiotic resistance Dogs Phenotypic Public health Staphylococcus aureus |
| title | Phenotypic Resistance of Staphylococcus aureus to Antibiotics in Dogs of Tamale Metropolis, Ghana |
| title_full | Phenotypic Resistance of Staphylococcus aureus to Antibiotics in Dogs of Tamale Metropolis, Ghana |
| title_fullStr | Phenotypic Resistance of Staphylococcus aureus to Antibiotics in Dogs of Tamale Metropolis, Ghana |
| title_full_unstemmed | Phenotypic Resistance of Staphylococcus aureus to Antibiotics in Dogs of Tamale Metropolis, Ghana |
| title_short | Phenotypic Resistance of Staphylococcus aureus to Antibiotics in Dogs of Tamale Metropolis, Ghana |
| title_sort | phenotypic resistance of staphylococcus aureus to antibiotics in dogs of tamale metropolis ghana |
| topic | Antibiotic resistance Dogs Phenotypic Public health Staphylococcus aureus |
| url | https://saa.rovedar.com/index.php/SAA/article/view/4 |
| work_keys_str_mv | AT frederickadzitey phenotypicresistanceofstaphylococcusaureustoantibioticsindogsoftamalemetropolisghana AT nicholasprah phenotypicresistanceofstaphylococcusaureustoantibioticsindogsoftamalemetropolisghana AT hafizsalifu phenotypicresistanceofstaphylococcusaureustoantibioticsindogsoftamalemetropolisghana AT davidyidana phenotypicresistanceofstaphylococcusaureustoantibioticsindogsoftamalemetropolisghana |