Acute toxicity study of Vilocym Premix (herbal growth promoter for Livestock)in Wistar Albino Rat

An experimental study with the objective of safety evaluation of Vilocym Premix, herbal growth promoter for Livestock (supplied by Ayurvet Ltd., Baddi, India), was done as per standard guidelines of OECD-423 for acute toxicity testing. Vilocym Premix is a scientifically developed combination of herb...

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Main Authors: A.H. Ahmad, D.S.Rekhe, K.Ravikanth, S.Maini
Format: Article
Language:English
Published: Veterinary World 2009-06-01
Series:Veterinary World
Subjects:
Online Access:http://www.scopemed.org/mnstemps/2/2-1273839375.pdf
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author A.H. Ahmad
D.S.Rekhe
K.Ravikanth
S.Maini
author_facet A.H. Ahmad
D.S.Rekhe
K.Ravikanth
S.Maini
author_sort A.H. Ahmad
collection DOAJ
description An experimental study with the objective of safety evaluation of Vilocym Premix, herbal growth promoter for Livestock (supplied by Ayurvet Ltd., Baddi, India), was done as per standard guidelines of OECD-423 for acute toxicity testing. Vilocym Premix is a scientifically developed combination of herbs that contains herbal ingredients namely Azadirachta indica, Curcuma longa & many more alongwith natural zeolites. The study was done in 3 males and 3 female Wistar Albino rats, which were administered an initial dose of 50 mg/kg body weight followed by dose rates of 300, 500 & 5000 mg/kg body weight of test compound. The animals were observed for signs of convulsions, tremors, circling, depression, excitement and mortality. Body weight was recorded at 0,7th and 14th day and plasma total protein, albumin; AST and ALT were measured after 3rd day of experiment. No abnormal sign of symptoms were observed in any of the animal fed with Vilocym Premix at the dose rate of 50, 300, 500 & 5000 mg/kg. No mortality was observed indicating safety of herbal premix. [Vet. World 2009; 2(3.000): 100-102]
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spelling doaj.art-3bdafa6700b34c31914501f754c972222022-12-21T19:32:00ZengVeterinary WorldVeterinary World0972-89882009-06-0123.000100102Acute toxicity study of Vilocym Premix (herbal growth promoter for Livestock)in Wistar Albino RatA.H. AhmadD.S.RekheK.RavikanthS.MainiAn experimental study with the objective of safety evaluation of Vilocym Premix, herbal growth promoter for Livestock (supplied by Ayurvet Ltd., Baddi, India), was done as per standard guidelines of OECD-423 for acute toxicity testing. Vilocym Premix is a scientifically developed combination of herbs that contains herbal ingredients namely Azadirachta indica, Curcuma longa & many more alongwith natural zeolites. The study was done in 3 males and 3 female Wistar Albino rats, which were administered an initial dose of 50 mg/kg body weight followed by dose rates of 300, 500 & 5000 mg/kg body weight of test compound. The animals were observed for signs of convulsions, tremors, circling, depression, excitement and mortality. Body weight was recorded at 0,7th and 14th day and plasma total protein, albumin; AST and ALT were measured after 3rd day of experiment. No abnormal sign of symptoms were observed in any of the animal fed with Vilocym Premix at the dose rate of 50, 300, 500 & 5000 mg/kg. No mortality was observed indicating safety of herbal premix. [Vet. World 2009; 2(3.000): 100-102]http://www.scopemed.org/mnstemps/2/2-1273839375.pdfGrowth PromoterHerbalLivestockToxicityProductionWeight gain
spellingShingle A.H. Ahmad
D.S.Rekhe
K.Ravikanth
S.Maini
Acute toxicity study of Vilocym Premix (herbal growth promoter for Livestock)in Wistar Albino Rat
Veterinary World
Growth Promoter
Herbal
Livestock
Toxicity
Production
Weight gain
title Acute toxicity study of Vilocym Premix (herbal growth promoter for Livestock)in Wistar Albino Rat
title_full Acute toxicity study of Vilocym Premix (herbal growth promoter for Livestock)in Wistar Albino Rat
title_fullStr Acute toxicity study of Vilocym Premix (herbal growth promoter for Livestock)in Wistar Albino Rat
title_full_unstemmed Acute toxicity study of Vilocym Premix (herbal growth promoter for Livestock)in Wistar Albino Rat
title_short Acute toxicity study of Vilocym Premix (herbal growth promoter for Livestock)in Wistar Albino Rat
title_sort acute toxicity study of vilocym premix herbal growth promoter for livestock in wistar albino rat
topic Growth Promoter
Herbal
Livestock
Toxicity
Production
Weight gain
url http://www.scopemed.org/mnstemps/2/2-1273839375.pdf
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