Design, Synthesis, and Evaluation of Alkyl-Quinoxalin-2(1<i>H</i>)-One Derivatives as Anti-<i>Quorum Sensing</i> Molecules, Inhibiting Biofilm Formation in <i>Aeromonas caviae</i> Sch3

Design, Synthesis, and Evaluation of Alkyl-Quinoxalin-2(1<i>H</i>)-One Derivatives as Anti-<i>Quorum Sensing</i> Molecules, Inhibiting Biofilm Formation in <i>Aeromonas caviae</i> Sch3

With the increasing antibiotic resistance of bacterial strains, alternative methods for infection control are in high demand. <i>Quorum sensing</i> (QS) is the bacterial communication system based on small molecules. QS is enables bacterial biofilm formation and pathogenic development. T...

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Bibliographic Details
Main Authors: René Blöcher, Ariel Rodarte Ramírez, Graciela Castro-Escarpulli, Everardo Curiel-Quesada, Alicia Reyes-Arellano
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Molecules
Subjects:
<i>anti-quorum sensing</i>
biofilm
quinoxalin-2(1<i>H</i>)-one
<i>Aeromonas caviae</i>
bioisosteres
Grignard reaction
Online Access:https://www.mdpi.com/1420-3049/23/12/3075

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