Yessotoxin, a Promising Therapeutic Tool
Yessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered a toxin. Modifications in second messenger levels, protein levels, immune cell...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2016-01-01
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| Series: | Marine Drugs |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1660-3397/14/2/30 |
| _version_ | 1798006020362993664 |
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| author | Amparo Alfonso Mercedes R. Vieytes Luis M. Botana |
| author_facet | Amparo Alfonso Mercedes R. Vieytes Luis M. Botana |
| author_sort | Amparo Alfonso |
| collection | DOAJ |
| description | Yessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered a toxin. Modifications in second messenger levels, protein levels, immune cells, cytoskeleton or activation of different cellular death types have been published as consequence of YTX exposure. This review summarizes the main intracellular pathways modulated by YTX and their pharmacological and therapeutic implications. |
| first_indexed | 2024-04-11T12:48:20Z |
| format | Article |
| id | doaj.art-3bde40899db044a3884166bdaed13fd7 |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-04-11T12:48:20Z |
| publishDate | 2016-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-3bde40899db044a3884166bdaed13fd72022-12-22T04:23:16ZengMDPI AGMarine Drugs1660-33972016-01-011423010.3390/md14020030md14020030Yessotoxin, a Promising Therapeutic ToolAmparo Alfonso0Mercedes R. Vieytes1Luis M. Botana2Department of Pharmacology, Faculty of Veterinary, University of Santiago of Compostela, 27002 Lugo, SpainDepartment of Physiology, Faculty of Veterinary, University of Santiago of Compostela, 27002 Lugo, SpainDepartment of Physiology, Faculty of Veterinary, University of Santiago of Compostela, 27002 Lugo, SpainYessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered a toxin. Modifications in second messenger levels, protein levels, immune cells, cytoskeleton or activation of different cellular death types have been published as consequence of YTX exposure. This review summarizes the main intracellular pathways modulated by YTX and their pharmacological and therapeutic implications.http://www.mdpi.com/1660-3397/14/2/30yessotoxin (YTX)apoptosisautophagycellular deathsignal transductioncytoskeletonimmune systemAlzheimerglucose metabolism |
| spellingShingle | Amparo Alfonso Mercedes R. Vieytes Luis M. Botana Yessotoxin, a Promising Therapeutic Tool Marine Drugs yessotoxin (YTX) apoptosis autophagy cellular death signal transduction cytoskeleton immune system Alzheimer glucose metabolism |
| title | Yessotoxin, a Promising Therapeutic Tool |
| title_full | Yessotoxin, a Promising Therapeutic Tool |
| title_fullStr | Yessotoxin, a Promising Therapeutic Tool |
| title_full_unstemmed | Yessotoxin, a Promising Therapeutic Tool |
| title_short | Yessotoxin, a Promising Therapeutic Tool |
| title_sort | yessotoxin a promising therapeutic tool |
| topic | yessotoxin (YTX) apoptosis autophagy cellular death signal transduction cytoskeleton immune system Alzheimer glucose metabolism |
| url | http://www.mdpi.com/1660-3397/14/2/30 |
| work_keys_str_mv | AT amparoalfonso yessotoxinapromisingtherapeutictool AT mercedesrvieytes yessotoxinapromisingtherapeutictool AT luismbotana yessotoxinapromisingtherapeutictool |