Immune Responses to Some Viral Infections That Have a High Evolutionary Potential—A Case Report with Literature Review

Viral infections are a key issue in modern medicine. SARS-CoV-2 infection confirms that we are not sufficiently prepared for these unforeseen infections. The COVID-19 pandemic has cultivated a great sense of fear and distrust in patients. If viral infections, in this case, SARS-CoV-2, overlap with a...

Full description

Bibliographic Details
Main Authors: Maria Lucia Sur, Bogdan-Stefan Moldovan, Diana Mocanu, Gabriel Samasca, Iulia Lupan, Ionel Armat, Marin Harabagiu, Genel Sur, Calin Lazar
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/12/7/940
_version_ 1827618855844839424
author Maria Lucia Sur
Bogdan-Stefan Moldovan
Diana Mocanu
Gabriel Samasca
Iulia Lupan
Ionel Armat
Marin Harabagiu
Genel Sur
Calin Lazar
author_facet Maria Lucia Sur
Bogdan-Stefan Moldovan
Diana Mocanu
Gabriel Samasca
Iulia Lupan
Ionel Armat
Marin Harabagiu
Genel Sur
Calin Lazar
author_sort Maria Lucia Sur
collection DOAJ
description Viral infections are a key issue in modern medicine. SARS-CoV-2 infection confirms that we are not sufficiently prepared for these unforeseen infections. The COVID-19 pandemic has cultivated a great sense of fear and distrust in patients. If viral infections, in this case, SARS-CoV-2, overlap with another infection, the symptoms are prolonged and worsened, and complications may occur. Starting from an objective clinical finding of a patient they had in follow-up and treatment, the authors present the problems of the diseases the patient suffered from. These are described as reviews so that readers can get an idea of the clinical methods of expression and the therapeutic possibilities. Therefore, this article describes Lyme disease and post-treatment Lyme disease syndrome, SARS-CoV-2 infection, and multisystem inflammatory syndrome in children (MISC-C), as the patient suffered from an incomplete form of Kawasaki disease. During the treatment for Lyme disease, the patient also contracted the influenza type A virus. Although any of these diseases could have the potential for serious evolution, our patient still went through these infections relatively well. This can be explained by the fact that the patient had a slow immune response to the aforementioned infections, which allowed him to survive these diseases relatively easily, unlike other individuals who have an exaggerated immune response or who suffer from serious immune involvement, e.g., hepatitis B with a fulminant response. The case was presented chronologically, but at the same time, all particular infection manifestations were accurately described. For these reasons, the article is presented in the form of a review, exemplified by the case itself. Of the 52 cases of MISC-C found in the Pediatrics Clinic II of Cluj-Napoca, we present the case of a male patient who presented with Lyme disease, post-treatment Lyme disease syndrome, Kawasaki disease, and MISC-C incomplete form.
first_indexed 2024-03-09T10:16:13Z
format Article
id doaj.art-3be1e488c63d4a5583661c69bd99a362
institution Directory Open Access Journal
issn 2075-1729
language English
last_indexed 2024-03-09T10:16:13Z
publishDate 2022-06-01
publisher MDPI AG
record_format Article
series Life
spelling doaj.art-3be1e488c63d4a5583661c69bd99a3622023-12-01T22:21:33ZengMDPI AGLife2075-17292022-06-0112794010.3390/life12070940Immune Responses to Some Viral Infections That Have a High Evolutionary Potential—A Case Report with Literature ReviewMaria Lucia Sur0Bogdan-Stefan Moldovan1Diana Mocanu2Gabriel Samasca3Iulia Lupan4Ionel Armat5Marin Harabagiu6Genel Sur7Calin Lazar8Department of Pediatric I, Iuliu Hatieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, RomaniaChildren’s Emergency Clinical Hospital, 400370 Cluj-Napoca, RomaniaChildren’s Emergency Clinical Hospital, 400370 Cluj-Napoca, RomaniaChildren’s Emergency Clinical Hospital, 400370 Cluj-Napoca, RomaniaMolecular Biology Department, Babes Bolyai University, 400084 Cluj-Napoca, RomaniaChildren’s Emergency Clinical Hospital, 400370 Cluj-Napoca, RomaniaDepartment of Pediatric I, Iuliu Hatieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, RomaniaChildren’s Emergency Clinical Hospital, 400370 Cluj-Napoca, RomaniaDepartment of Pediatric I, Iuliu Hatieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, RomaniaViral infections are a key issue in modern medicine. SARS-CoV-2 infection confirms that we are not sufficiently prepared for these unforeseen infections. The COVID-19 pandemic has cultivated a great sense of fear and distrust in patients. If viral infections, in this case, SARS-CoV-2, overlap with another infection, the symptoms are prolonged and worsened, and complications may occur. Starting from an objective clinical finding of a patient they had in follow-up and treatment, the authors present the problems of the diseases the patient suffered from. These are described as reviews so that readers can get an idea of the clinical methods of expression and the therapeutic possibilities. Therefore, this article describes Lyme disease and post-treatment Lyme disease syndrome, SARS-CoV-2 infection, and multisystem inflammatory syndrome in children (MISC-C), as the patient suffered from an incomplete form of Kawasaki disease. During the treatment for Lyme disease, the patient also contracted the influenza type A virus. Although any of these diseases could have the potential for serious evolution, our patient still went through these infections relatively well. This can be explained by the fact that the patient had a slow immune response to the aforementioned infections, which allowed him to survive these diseases relatively easily, unlike other individuals who have an exaggerated immune response or who suffer from serious immune involvement, e.g., hepatitis B with a fulminant response. The case was presented chronologically, but at the same time, all particular infection manifestations were accurately described. For these reasons, the article is presented in the form of a review, exemplified by the case itself. Of the 52 cases of MISC-C found in the Pediatrics Clinic II of Cluj-Napoca, we present the case of a male patient who presented with Lyme disease, post-treatment Lyme disease syndrome, Kawasaki disease, and MISC-C incomplete form.https://www.mdpi.com/2075-1729/12/7/940viral infectionsinfectious associationstreatment
spellingShingle Maria Lucia Sur
Bogdan-Stefan Moldovan
Diana Mocanu
Gabriel Samasca
Iulia Lupan
Ionel Armat
Marin Harabagiu
Genel Sur
Calin Lazar
Immune Responses to Some Viral Infections That Have a High Evolutionary Potential—A Case Report with Literature Review
Life
viral infections
infectious associations
treatment
title Immune Responses to Some Viral Infections That Have a High Evolutionary Potential—A Case Report with Literature Review
title_full Immune Responses to Some Viral Infections That Have a High Evolutionary Potential—A Case Report with Literature Review
title_fullStr Immune Responses to Some Viral Infections That Have a High Evolutionary Potential—A Case Report with Literature Review
title_full_unstemmed Immune Responses to Some Viral Infections That Have a High Evolutionary Potential—A Case Report with Literature Review
title_short Immune Responses to Some Viral Infections That Have a High Evolutionary Potential—A Case Report with Literature Review
title_sort immune responses to some viral infections that have a high evolutionary potential a case report with literature review
topic viral infections
infectious associations
treatment
url https://www.mdpi.com/2075-1729/12/7/940
work_keys_str_mv AT marialuciasur immuneresponsestosomeviralinfectionsthathaveahighevolutionarypotentialacasereportwithliteraturereview
AT bogdanstefanmoldovan immuneresponsestosomeviralinfectionsthathaveahighevolutionarypotentialacasereportwithliteraturereview
AT dianamocanu immuneresponsestosomeviralinfectionsthathaveahighevolutionarypotentialacasereportwithliteraturereview
AT gabrielsamasca immuneresponsestosomeviralinfectionsthathaveahighevolutionarypotentialacasereportwithliteraturereview
AT iulialupan immuneresponsestosomeviralinfectionsthathaveahighevolutionarypotentialacasereportwithliteraturereview
AT ionelarmat immuneresponsestosomeviralinfectionsthathaveahighevolutionarypotentialacasereportwithliteraturereview
AT marinharabagiu immuneresponsestosomeviralinfectionsthathaveahighevolutionarypotentialacasereportwithliteraturereview
AT genelsur immuneresponsestosomeviralinfectionsthathaveahighevolutionarypotentialacasereportwithliteraturereview
AT calinlazar immuneresponsestosomeviralinfectionsthathaveahighevolutionarypotentialacasereportwithliteraturereview