De novo design of a novel AIE fluorescent probe tailored to autophagy visualization via pH manipulation

Abstract Background Macroautophagy is an essential cellular self-protection mechanism, and defective autophagy has been considered to contribute to a variety of diseases. During the process, cytoplasmic components are transported via autophagosomes to acidic lysosomes for metabolism and recycling, w...

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Bibliographic Details
Main Authors: Xueyan Huang, Fei Chen, Yeshuo Ma, Fan Zheng, Yanpeng Fang, Bin Feng, Shuai Huang, Hongliang Zeng, Wenbin Zeng
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2023-03-01
Series:Biomaterials Research
Subjects:
Online Access:https://doi.org/10.1186/s40824-023-00359-w